腹腔镜下胆囊癌根治术的有效性及安全性研究  

Efficacy and Safety Study of Laparoscopic Radical Surgery of Gallbladder Cancer in the Treatment of Gallbladder Cancer

作　　者：王伟 别玉坤[2] 尹余余 WANG Wei;BIE Yukun;YIN Yuyu(Xingyuan Hospital,Yulin,719000)

机构地区：[1]陕西省榆林市星元医院,719000 [2]陕西省安康市中心医院,725000

出　　处：《实用癌症杂志》2020年第4期609-611,642,共4页The Practical Journal of Cancer

摘　　要：目的探讨腹腔镜下胆囊癌根治术的有效性及安全性。方法选取67例胆囊癌患者为研究对象,根据入院单双号将受试者进行分组,其中对照组33例患者接受传统的开腹胆囊癌根治术治疗,研究组34例患者接受腹腔镜下胆囊癌根治术治疗。比较2组患者的手术情况、手术前后各炎性因子水平及并发症发生率;随访3年后,比较2组患者的生存率。结果2组淋巴结清扫数量比较无统计学差异(P>0.05);研究组患者的切口长度、手术时间、术中出血量以及术后各康复指标均显著优于对照组(P<0.05)。与术前相比,术后第3天2组患者各炎性因子水平均明显降低,且研究组显著低于对照组(P<0.05)。研究组患者术后并发症发生率显著低于对照组(P<0.05)。2组患者术后6个月、1年、3年生存率比较,无统计学差异(P>0.05)。结论腹腔镜下胆囊癌根治术对机体损伤小,炎症反应轻微,术后并发症少,患者恢复快,手术安全可靠,值得临床推广应用。Objective To explore efficacy and safety study of laparoscopic radical surgery of gallbladder cancer in the treatment of gallbladder cancer.Methods 67 patients with gallbladder carcer were selected as the subjects.According to the admission single and double number,all patients were divided into the control group and the study group.33 cases of the control group received conventional open radical gallbladder cancer radical treatment,34 cases of the study group received laparoscopic radical surgery of gallbladder cancer.Surgery,inflammatory factor levels and complication rates before and after surgery.After 3 years of follow-up,the survival rates of the 2 groups were compared.Results There was no significant difference in the number of lymph node dissection between the 2 groups(P>0.05).The incision length,operation time,intraoperative blood loss and postoperative rehabilitation indexes of the study group were significantly better than the control group(P<0.05).Comparing with preoperative,the levels of inflammatory factors in the 2 groups were significantly lower on the 3rd day postoperative,the study group was significantly lower than the control group(P<0.05).The incidence of postoperative complications was significantly lower in the study group than of the control group(P<0.05).There was no significant difference in the 6-month,1-year,and 3-year survival rates postoperative between the 2 groups(P>0.05).Conclusion Laparoscopic adical surgery of gallbladder cancer has little damage to the body,mild inflammation,less postoperative complications,and rapid recover,the surgical effect is safe and reliable in the treatment of gallbladder cancer,and it is worthy of clinical application.

关 键 词：腹腔镜 胆囊癌根治术 胆囊癌 炎性因子 生存率 并发症 

分 类 号：R735.8[医药卫生—肿瘤]