升降汤加减治疗食管癌术后胃肠功能紊乱临床研究  

Clinical Study on Modified Shengjiang Tang for Gastrointestinal Dysfunction after Operation for Esophageal Carcinoma

作　　者：樵小健 缑一杰 李刚 李宏[1] 姚树雄 马贵能 刘伟 QIAO Xiaojian;GOU Yijie;LI Gang;LI Hong;YAO Shuxiong;MA Guineng;LIU Wei

机构地区：[1]天水市第二人民医院胸心外科,甘肃天水741020

出　　处：《新中医》2020年第5期37-39,共3页New Chinese Medicine

摘　　要：目的:观察升降汤加减治疗食管癌术后胃肠功能紊乱的临床效果。方法:选取160例食管癌术后胃肠功能紊乱患者,按随机数字表法分为治疗组和对照组各80例。2组患者术后给予常规治疗及对症处理,对照组给予多潘立酮片口服,治疗组在对照组基础上加用升降汤加减治疗。观察2组临床疗效及症状评分变化,采用癌症患者生活质量测定量表(EORTC QLQ-C30)评估患者生活质量。结果:治疗组总有效率为93.75%,高于对照组61.67%(P<0.05)。治疗前,2组腹痛、恶心呕吐、上腹胀、伴随症状评分比较,差异无统计学意义(P>0.05)。治疗后,2组腹痛、恶心呕吐、上腹胀、伴随症状评分较治疗前降低(P<0.05),且治疗组腹痛、恶心呕吐、上腹胀、伴随症状评分低于对照组(P<0.05)。治疗前,2组生活质量各项评分比较,差异无统计学意义(P>0.05)。治疗后,2组生活质量各项评分较治疗前升高(P<0.05),且治疗组生活质量各项评分高于对照组(P<0.05)。结论:升降汤加减治疗食管癌术后胃肠功能紊乱,可显著改善患者相关临床症状,患者术后生活质量得到改善,总体预后效果较好。Objective:To observe the clinical effect of modified Shengjiang tang for gastrointestinal dysfunction after the operation for esophageal carcinoma.Methods:A total of 160 cases of patients with gastrointestinal dysfunction after the operation for esophageal carcinoma were selected and divided into the treatment group and the control group according to the random number table method,80 cases in each group.After operation,both groups were given routine treatment and expectant treatment;the control group was given the oral administration of doperidone tablets,and the treatment group was additionally given modified Shengjiang tang based on the treatment of the control group.The improvement of symptoms,the total curative effect,and the changes of clinical effect and symptom scores in the two groups were observed,and the quality of life was evaluated by European Organization for Research Treatment of Cancer Quality of Life Questionnaire(EORTC QLQ-C30).Results:The total effective rate was 93.75%in the treatment group,higher than that of 61.67%in the control group(P<0.05).Before treatment,compared the scores of abdominal pain,nausea and vomiting,upper abdominal distension and concomitant symptoms in the two groups,there was no significance in the difference(P>0.05).After treatment,the above scores in the two groups were all decreased when compared with those before treatment(P<0.05),and the above scores in the treatment group were lower than those in the control group(P<0.05).Before treatment,compared all the scores of quality of life in the two groups,there was no significance in the difference(P>0.05).After treatment,all the scores of quality of life in the two groups were increased when compared with those before treatment(P<0.05),and the above scores in the treatment group were higher than those in the control group(P<0.05).Conclusion:The therapy of modified Shengjiang tang for gastrointestinal dysfunction after the operation for esophageal carcinoma can significantly improve the related clinical symptoms and the qual

关 键 词：食管癌 手术 胃肠功能紊乱 升降汤 临床症状 癌症患者生活质量测定量表(EORTC QLQ-C30) 

分 类 号：R735.1[医药卫生—肿瘤]