铜催化下苄胺与2-甲基喹啉化合物的需氧氧化烯化反应  

Cu-Catalyzed Aerobic Oxidative Olefination of Benzyl Amines with 2-Methylquinolines

作　　者：于静 燕然 周坤洁 马瑞甜 曹新华[1] 马献涛 YU Jing;YAN Ran;ZHOU Kunjie;MA Ruitian;CAO Xinhua;MA Xiantao(College of Chemistry and Chemical Engineering/Green Catalysis&Synthesis Key Laboratory of Xinyang City,Xinyang Normal University,Xinyang 464000,China)

机构地区：[1]信阳师范学院化学化工学院/信阳市绿色催化与合成重点实验室,河南信阳464000

出　　处：《信阳师范学院学报（自然科学版）》2020年第2期281-285,共5页Journal of Xinyang Normal University(Natural Science Edition)

基　　金：河南省科技攻关项目(192102310031);信阳师范学院青年骨干教师资助计划(2018GGJS-05);信阳师范学院大学生科研基金资助(2019-DXS-026)。

摘　　要：以廉价的铜试剂作为催化剂、以空气作为单一的氧化剂,发展了苄胺的需氧氧化新方法,用于高效、绿色制备烯基喹啉化合物,产率32%~80%.与文献方法相比,该方法催化体系简单易得、反应高效、副产物少,可以兼容MeO、NO 2、F、Cl等一系列官能团.Cu-catalyzed aerobic oxidative olefination of benzyl amines with 2-methylquinoline was developed for the green and efficient synthesis of 2-styrylquinolines with 32%~80%yields.This method requires air as the sole oxidant,cheap and easily-available CuI as the catalyst,and can tolerate various functional groups such as MeO,NO 2,F,Cl etc.

关 键 词：苄胺 甲基喹啉 需氧氧化 铜催化 

分 类 号：O626[理学—有机化学]