文拉法辛缓释剂对抑郁症患者认知功能的影响  

Effect of venlafaxine sustained release agent on cognitive function of patients with depression

作　　者：李志鹏[1] Li Zhipeng(Yunnan Psychiatric Hospital,Yunnan Kunming 650224)

机构地区：[1]云南省精神病医院,云南昆明650224

出　　处：《中国社区医师》2020年第11期51-51,53,共2页Chinese Community Doctors

摘　　要：目的:探讨文拉法辛缓释剂对抑郁症患者认知功能的影响效果。方法:2018年3月-2019年2月收治抑郁症患者76例,随机分为两组,各38例。对照组服用艾司西酞普兰治疗;观察组给予文拉法辛缓释释片治疗。比较两组疗效。结果:观察组治疗后汉密尔顿抑郁量表(HAMD-17)和威斯康星卡片(WCST)认知功能评分明显低于对照组,观察组总有效率优于对照组,差异均有统计学意义(P<0.05)。结论:文拉法辛缓释剂能够较好地改善抑郁症患者认知功能,提高临床治疗效果。Objective:To explore the effect of venlafaxine sustained release agent on cognitive function in patients with depression.Methods:76 patients with depression were selected from March 2018 to February 2019,they were randomly divided into the two groups with 38 cases in each group.The control group was treated with escitalopram,the observation group was treated with sustained release agent.The curative effect of the two groups was compared.Results:After treatment,the cognitive function scores of Hamilton depression scale and wisconsin card(WCST)in the observation group were significantly lower than those in the control group,the total effective rate of the observation group was better than that of the control group,the differences were statistically significant(P<0.05).Conclusion:Venlafaxine sustained release agent can improve the cognitive function of depression patients and improve the clinical treatment effect.

关 键 词：文拉法辛缓释剂 抑郁症 认知功能 

分 类 号：R749.4[医药卫生—神经病学与精神病学]