乳腺叶状肿瘤临床病理特点及误诊原因分析  

Clinicopathological characteristics and causes of misdiagnosis of phyllodes tumor of breast

作　　者：袁继华[1] Yuan Jihua(Department of Pathology,the People's Hospital of Shimen County,Changde City,Hunan Province,Hunan Changde 415300)

机构地区：[1]湖南省常德市石门县人民医院,湖南常德415300

出　　处：《中国社区医师》2020年第11期82-83,共2页Chinese Community Doctors

摘　　要：目的:探讨乳腺叶状肿瘤的临床病理特点及误诊原因。方法:2015年1月-2019年10月选取误诊患者29例,对所有手术标本均做冰冻切片和术后石蜡切片进行病理诊断,分析诊断结果。结果:最终病理诊断结果为诊断恶性分叶状肿瘤9例(31.09%),3例为复发病例,6例为首次就诊。其中病变累及皮肤和乳头3例,伴有平滑肌肉瘤和未分化肉瘤成分3例,伴骨肉瘤和软骨肉瘤成分3例。最终诊断交界性叶状肿瘤10例(34.5%),均为复发病例。最终诊断乳腺良性叶状肿瘤10例(34.5%),其中6例为复发病例。结论:乳腺叶状肿瘤是从良性、交界性到恶性的谱系性疾病,临床表现和影像学检查无特征性,临床误诊率高,结合临床病理特点和免疫组化可以提高正确诊断率。Objective:To explore the clinicopathological characteristics and causes of misdiagnosis of phyllodes tumor of breast.Methods:From January 2015 to October 2019,29 misdiagnosed patients were selected.All the surgical specimens were frozen and paraffin sections for pathological diagnosis.We analyzed the diagnosis results.Results:The final pathological diagnosis was malignant lobular tumor in 9 cases(31.09%),there were 3 cases of recurrence and 6 cases of first visit.The lesions involved skin and nipple in 3 cases,there were 3 cases with leiomyosarcoma and undifferentiated sarcoma,3 cases with osteosarcoma and chondrosarcoma.Finally,10 cases(34.5%)were diagnosed as borderline phyllodes tumor,all of them were relapsed.Finally,10 cases(34.5%)of breast benign phyllodes tumor were diagnosed among which 6 cases were recurrent.Conclusion:Phyllodes tumor of breast is a lineage disease from benign,borderline to malignant,the clinical manifestations and imaging examination have no characteristics,and the clinical misdiagnosis rate is high,combined with clinicopathological features and immunohistochemistry,the correct diagnosis rate can be improved.

关 键 词：乳腺叶状肿瘤 病理特点 误诊原因 

分 类 号：R737.9[医药卫生—肿瘤]