Comparison of cell salvage with one and two suction devices during cesarean section in patients with placenta previa and/or accrete: a randomized controlled trial  

作　　者：Hong Chen Hua Tan Pei-Xin Luo Yi-Fang Shen Chang-Cheng Lyu Xiao-Wei Qian Xin-Zhong Chen 

机构地区：[1]Department of Anesthesia,Women's Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang 310006,China [2]Department of Clinical Laboratory,Women's Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang 310006,China

出　　处：《Chinese Medical Journal》2020年第6期638-643,共6页中华医学杂志（英文版）

基　　金：This work was supported by grants from the National Natural Science Foundation of China(No.81471126 and No.81870868).

摘　　要：Background:Cell salvage has recently been recommended for obstetric use in cases with a high risk of massive hemorrhage during cesarean section(CS).However,limited data are available to support the use of one suction device to collect lost blood.This study aimed to investigate the volume of red blood cells(RBCs)salvaged and the components of amniotic fluid(AF)in blood salvaged by one suction device or two devices during CS in patients with placenta previa and/or accrete.Methods:Thirty patients with placenta previa and/or accrete undergoing elective CS in the Women's Hospital of Zhejiang University School of Medicine were recruited for the present study from November 1,2017 to December 1,2018.The patients were randomly assigned to one of the two groups according to an Excel-generated random number sheet:Group 1(w=15),in which only one suction device was used to aspirate all blood and AF,and Group 2(w=15),in which a second suction device was mainly used to aspirate AF before the delivery of the placenta.Three samples of blood per patient(pre-wash,post-wash,and post-filtration)were collected to measure AF components.The salvaged RBC volumes were recorded.Continuous data of pre-wash,post-wash,and postfiltration samples were analyzed by using one-way analysis of variance with Tukey5s test for multiple comparisons,or Kruskal-Wallis test with Dunn test for multiple comparisons.Comparisons of continuous data between Group 1 and Group 2 were conducted using Student's t test or Mann-Whitney U test.Results:The salvaged RBC volume was significantly higher in Group 1 than that in Group 2(401.6±77.2 mL vs.330.1土53.3 mL,?=4.175,P<0.001).In both groups,squamous cells,lamellar bodies,and fat were significantly reduced by washing(all P<0.001)and squamous cells were further reduced by filtering(P<0.001).Squamous cells were found in six post-filtration samples(three from each group).Lamellar bodies and fat were completely removed by filtering.Insulin-like growth factor binding protein 1,alphafetoprotein,albumin,lactate dehydrogen

关 键 词：Cell SALVAGE BLOOD TRANSFUSION PLACENTA previa PLACENTA accrete CESAREAN section 

分 类 号：R719[医药卫生—妇产科学]