牙囊在牙萌出的作用及其调控机制研究进展  

Research Progress on Effects of Dental Follicle during Tooth Eruption and the Regulatory Mechanism

作　　者：何梦婷 白丁[1] HE Mengting;BAI Ding(State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.)

机构地区：[1]口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心四川大学,华西口腔医院正畸科,四川成都610041

出　　处：《口腔医学研究》2020年第2期107-110,共4页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:81371171)。

摘　　要：牙齿的萌出是指牙齿从颌骨内向口腔移动,穿透颌骨与口腔黏膜,然后接触对颌牙达到功能位置的复杂过程,这一过程在时间和空间上均受到严格管控。牙囊是围绕在发育中牙胚周围的一层来源于外胚间充质的疏松结缔组织,它通过招募单核细胞以及调控骨吸收和骨形成在牙齿萌出过程中发挥关键作用。国内外学者对牙囊在牙齿萌出中的作用和机制研究甚多,现将研究进展作一综述。Tooth eruption is a series of complicated physiological processes that the tooth moves through the alveolar bone and the oral mucosa until it finally reaches the functional position.The eruption process is strictly controlled in time and space.The dental follicle,a layer of loose connective tissue from ectomesenchyme surrounding the developing tooth germ,is necessary for tooth eruption.It plays a key role in the tooth eruption by recruiting monocytes and regulating bone resorption and formation.Hence,this review describes the recent research progress on the effects and regulatory mechanism of dental follicle during tooth eruption.

关 键 词：牙囊 牙齿萌出 破骨细胞 成骨分化 

分 类 号：R78[医药卫生—口腔医学]