西南地区两个病理中心14年494例牙源性肿瘤回顾性研究  

Odontogenic Tumors in Southwest China Over a 14-year Retrospective Study of 494 Cases

作　　者：钱叶梅 潘国庆[2] 王卫红[1] 娄慧全 李静宜 张哲 QIAN Yemei;PAN Guoqing;WANG Weihong;LOU Huiquan;LI Jingyi;ZHANG Zhe(Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital of Kunming Medical University, Kunming 650106, China;Department of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming 650031, China;Department of Oral and Maxillofacial Surgery, First People's Hospital of Yunnan Province, Kunming 650302, China.)

机构地区：[1]昆明医科大学附属口腔医院口腔颌面外科,云南昆明650106 [2]昆明医科大学第一附属医院病理科,云南昆明650031 [3]云南省第一人民医院口腔颌面外科,云南昆明650302

出　　处：《口腔医学研究》2020年第2期164-166,共3页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:81660187);昆明医科大学创新团队项目(编号:CXTD201711)。

摘　　要：目的:探讨中国西南地区的牙源性肿瘤发病情况及临床病理特点,并与其它地区牙源性肿瘤流行特点进行对比分析,为牙源性肿瘤风险群体、临床诊断以及牙源性肿瘤相关研究提供依据。方法:回顾性分析2005年1月~2019年4月期间在昆明医科大学附属口腔医院和云南省第一人民医院就诊的494例牙源性肿瘤患者的临床病理资料,对比中国西南地区与其它地区流行病学状况的区别。结果:中国西南地区494例牙源性肿瘤患者中,男性271例(54.9%),女性223例(45.1%),男女性别比为1.22∶1。牙源性肿瘤平均年龄(32.99±15.96)岁。良性484例(98%),恶性10例(2%)。其中成釉细胞瘤多见,占403例(81.6%),其次是牙瘤34例(6.9%)。牙源性肿瘤发生于下颌骨与上颌骨之比为5.1∶1,413例(83.6%)发于下颌骨。结论:中国西南地区牙源性肿瘤以成釉细胞瘤最多见,多发于年轻男性下颌骨。中国西南地区牙源性肿瘤和成釉细胞瘤发生率大约分别为0.98和0.80人/100万人。Objective:To investigate the clinicopathologic features of odontogenic tumors(OTs)in southwest China and compare the epidemiologic characteristics of OTs with other areas in order to provide assistance in clinical diagnosis and related research of OTs.Methods:494 patients with OTs from January 2005 to April 2019 were retrospectively analyzed and the differences in epidemiological status were compared with other areas.Results:Among 494 OTs patients in southwest China,271(54.9%)were males and 223(45.1%)were females.The male-to-female ratio was 1.22∶1.The average age of OTs was(32.99±15.96)years.484 cases(98%)of OTs were benign,and 10 cases(2%)were malignant.Among all OTs,ameloblastoma(AME)was the most common,accounting for 403 cases(81.6%),followed by 34 cases(6.9%)of Odontomas.The mandible-to-maxilla ratio of OTs was 5.1∶1,and 413 cases(83.6%)occurred in the mandible.Conclusion:The most common OTs in southwest China is AME,especially in young males'mandibles.The incidence of OTs and AME in southwest China is about 0.98 and 0.80 per million person-years,respectively.

关 键 词：牙源性肿瘤 临床病理分析 流行病学 中国西南地区 

分 类 号：R73[医药卫生—肿瘤]