静脉溶栓在治疗脑梗塞的临床效果及脑出血发病率研究  

Clinical Effect of Intravenous Thrombolysis in the Treatment of Cerebral Infarction and the Incidence of Cerebral Hemorrhage

作　　者：谢意[1] XIE Yi(Department of Neurology of People and Wish in Huadian City,Huadiau,Jilin Province,132400 China)

机构地区：[1]吉林省桦甸市人民医院神经内科,吉林桦甸132400

出　　处：《中外医疗》2020年第3期63-65,共3页China & Foreign Medical Treatment

摘　　要：目的探讨和研究超早期脑梗塞尿激酶静脉溶栓的策略后的治疗效果及脑出血发病率。方法选方便取该院于2017年6月-2018年12月收治的超早期脑梗塞溶栓患者35例作为研究对象,将其定为实验组;并把同阶段且同标准的非溶栓处置的患者35例划定为对照组,实验组进行静脉溶栓,对照组给予常规治疗,然后仔细观察记录患者PT(凝血酶原时间)和FIB(纤维蛋白原)以及TT(凝血酶时间)。结果实验组的总有效是71.43%,显著高于对照组(25.71%),组间对比差异有统计学意义(χ~2=5.907,P<0.05);实验组溶栓前的FIB(纤维蛋白原)为(4.91±1.63)g/L,显著大于溶栓后;实验组溶栓后的FIB(纤维蛋白原)为(4.91±1.63)g/L,TT(凝血酶时间)、PT(凝血酶原时间)分别是(17.06±2.19)s、(12.07±4.17)s,都显著优于溶栓前;实验组溶栓前后的上述指标对比差异有统计学意义(P<0.05);实验组脑出血发病率是17.14%,显著高于对照组,组间对比差异有统计学意义(χ~2=6.142,P<0.05)。结论对超早期脑梗塞患者选择尿激酶静脉溶栓的策略,效果较为理想;但会显示脑出血,且呈现于溶栓24 h中,故此,需要预先对此症状做到科学的预测,以便及时进行诊断治疗。Objective To explore and study the therapeutic effect and incidence of cerebral hemorrhage after intravenous thrombolysis with urokinase in super-early cerebral infarction. Methods Thirty-five patients Convenient selection with thrombolysis in ultra-early cerebral infarction treated in the hospital from June 2017 to December 2018 were selected as the research object, and they were designated as the experimental group;35 patients with non-thrombolytic treatment at the same stage and with the same standard were selected The case was designated as the control group, the experimental group was treated with intravenous thrombolysis, and the control group was given conventional treatment, and then the patients’ PT(prothrombin time) and FIB(fibrinogen) and TT(thrombin time) were carefully observed and recorded. Results The total effectiveness of the experimental group was 71.43%, which was significantly higher than that of the control group(25.71%).There was a statistically significant difference in the total effective rate between the two groups(χ~2=5.907, P<0.05);the experimental group had thrombolysis The former FIB(fibrinogen) was(4.91±1.63) g/L, which was significantly larger than that after thrombolysis;the FIB(fibrinogen) after thrombolysis in the experimental group was(4.91±1.63) g/L, and TT(thrombin)Time) and PT(prothrombin time) were(17.06 ±2.19)s and(12.07±4.17)s, which were significantly better than those before thrombolysis;the above indexes before and after thrombolysis were statistically significantly different in the experimental group(P<0.05);the incidence of cerebral hemorrhage in the experimental group was 17.14%, which was significantly higher than that in the control group. There was a statistically significant difference in the incidence of cerebral hemorrhage between the two groups(χ~2=6.142, P<0.05). Conclusion Urokinase intravenous thrombolysis is an ideal strategy for patients with super-early cerebral infarction, but it will show cerebral hemorrhage and appear in 24 hours of thrombolys

关 键 词：脑梗塞 尿激酶 静脉溶栓 脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]