不明原因急诊腹痛患者中非霍奇金淋巴瘤肠道浸润的18F-氟代葡萄糖正电子发射计算机体层显像仪影像学表现  

18F-fluorodeoxyglucose positron emission computed tomography findings of intestinal infiltration of non-hodgkin lymphoma in patients with unexplained emergency abdominal pain

作　　者：陈彩龙[1] 林美福[1] 陈文新[1] 周硕[1] 曹登敏 陈国宝[1] 李君霞[1] CHEN Cai-long;LIN Mei-fu;CHEN Wen-xin;ZHOU Shuo;CAO Deng-min;CHEN Guo-bao;LI Jun-xia(Department of Nuclear Medicine,Fujian Provincial Hospital,Fuzhou 350001,China)

机构地区：[1]福建省立医院核医学科,福州350001

出　　处：《创伤与急诊电子杂志》2019年第4期200-204,共5页Journal of Trauma and Emergency(Electronic Version)

摘　　要：目的分析总结不明原因急诊腹痛患者中非霍奇金淋巴瘤肠道浸润的18F-氟代葡萄糖(18F-fluorodeoxyglucose,18F-FDG)正电子发射计算机体层显像仪(positron emission computed tomography,PET/CT)影像学特征及探讨其临床应用价值。方法回顾性分析2012年9月至2018年5月在福建省立医院病理确诊为非霍奇金淋巴瘤肠道浸润并行18F-FDG PET/CT检查的21例不明原因急诊腹痛患者影像资料,分析总结其病灶部位、大小、放射性分布等影像特征。结果21例患者中病灶均清晰全面显示,敏感性达100%,其中弥漫大B细胞淋巴瘤14例,T细胞淋巴瘤6例,惰性淋巴瘤1。影像特征如下:①部位分布中小肠单发病灶8例,多发病灶3例;结肠单发2例,多发1例,回盲部单发2例,回盲部合并小肠3例;结肠合并小肠多发2例。②肠壁增厚厚度为0.8~11.2cm(平均2.23cm),标准摄取值(standard uptake value,SUV)4.2~43.7(平均13.79);肠腔扩张表现3例。③无合并肠管外其他部位淋巴瘤浸润4例;肠管外其他部位淋巴瘤浸润17例,其中全身淋巴结多发浸润5例,全身淋巴结及皮下浸润2例,全身淋巴结、肝脏、脾脏及骨骼浸润2例,腹腔淋巴结浸润3例,肺部及甲状腺浸润1例,全身淋巴结及骨骼浸润1例,肝脏1例,胃1例,腹腔淋巴结及脾脏浸润1例。④4例肠道淋巴瘤术后患者,检查后均发现其他部位淋巴瘤浸润。⑤5例复查患者,病灶及代谢基本消失4例,复发1例。结论非霍奇金淋巴瘤肠道浸润18F-FDG PET/CT显像表现为肠壁增厚及明显放射性异常浓聚,部分表现为特异性瘤样扩张,在此类不明原因急诊腹痛患者诊断中具有较高临床应用价值。Objective To analyze the imaging characteristics of 18F-fluorodeoxyglucose(18F-FDG)PET/CT for intestinal infiltration of non-hodgkin lymphoma in patients with unexplained emergency abdominal pain and discuss its clinical application value.Methods The imaging data of 21 patients with unexplained abdominal pain who were pathologically diagnosed with intestinal infiltration of non-Hodgkin lymphoma and underwent 18F-FDG PET/CT examination in our hospital from September 2012 to May 2018 were retrospectively analyzed,and the imaging characteristics such as lesion location,size and radioactive distribution were analyzed and summarized.Results The lesions were clearly and comprehensively displayed in all 21 patients,with a sensitivity of 100%,including 14 patients with diffuse large B-cell lymphoma,6 patients with T-cell lymphoma,and 1 patient with inert lymphoma,and the imaging features were as follows:①Location distribution:there were 8 cases of a single lesion in the small intestine including 2 cases in the colon,2 cases in the ileocecal region and 3 cases in ileocecal region combined with small intestine,and 3 cases of multiple lesions including 1 case in the colon as well as 2 cases in the colon combined with small intestine.②Intestinal wall thickening ranged from 0.8cm to 11.2cm and standard uptake value(SUVmax)was 4.2 to 43.7(mean value 13.79).There were 3 cases of intestinal dilatation.③There were 4 cases of no infiltration of lymphoma at other sites outside the intestinal canal,17 cases of bowel lymphoma infiltration at other sites including 5 cases of frequent systemic lymph node invasion,2 cases of systemic lymph nodes and subcutaneous infiltration,2 cases of systemic lymph nodes,liver,spleen and bone invasion,3 cases of abdominal lymph node invasion,1 case of lung and thyroid infiltration,1 case of systemic lymph node and bone infiltration,1 case in the liver,1 case in the stomach,and 1 case of abdominal lymph nodes and spleen infiltration.④Four cases of postoperative lymphoma of the intestine were fo

关 键 词：肠道淋巴瘤 18F-氟代葡萄糖 正电子发射断层扫描 诊断 

分 类 号：R735[医药卫生—肿瘤]