国人版角膜接触镜配戴者生活质量量表的研制与评估  

Development and Evaluation of Contact Lens Impact on the Chinese Version of the Quality of Life Questionnaire

作　　者：李天坤 黄锦海[1,2] 许琛琛 陈海丝[1,2] 李坤珂 王勤美[1,2] 高蓉蓉 Tiankun Li;Jinhai Huang;Chenchen Xu;Haisi Chen;Kunke Li;Qinmei Wang;Rongrong Gao(Wenzhou Medical University,Wenzhou 325035,China;Eye Hospital,Wenzhou Medical University,Wenzhou 325027,China)

机构地区：[1]温州医科大学,325035 [2]温州医科大学附属眼视光医院,325027

出　　处：《中华眼视光学与视觉科学杂志》2020年第2期111-118,共8页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：浙江省医药卫生科技计划项目(Y2017KY495);温州市科技计划项目(Y20170195);浙江省大学生科技创新活动计划(新苗人才计划)项目(2015R413014)。

摘　　要：目的:研制国人版角膜接触镜配戴者生活质量量表(CLIQ)并评估其信度和效度,分析得分的影响因素。方法:采用横断面研究。对英国原版CLIQ进行翻译、回译、文化调试,形成国人版量表。选择2015年4─12月在温州医科大学附属眼视光医院就诊的角膜接触镜配戴者205例进行问卷调查,其中再随机选取20例由2名调查员分别进行调查,对问卷数据进行统计分析。结果:回收有效问卷201例。视功能维度因应答率小于50%被删除。量表Cronbach'sα系数为0.77,眼部症状维度为0.68,便利性、经济和情感维度均>0.7,量表Guttmann Split-Half系数为0.89,眼部症状、便利性、经济和情感维度分别为0.75、0.78、0.65和0.93。认知维度Cronbach'sα系数和Guttmann Split-Half系数均为0.49故被删除;删除条目20后健康关注维度Cronbach'sα系数和Guttmann Split-Half系数分别为0.68和0.73。2名调查员之间的评分结果高度相关(r=0.87~0.99,P<0.001)。各条目的条目水平内容效度指数为0.83~1.00,量表的平均水平内容效度指数为0.95。探索性因子分析提取的5个因子分别对应各维度,累计方差贡献率60.43%。眼部症状维度与年龄(r=-0.153,P=0.03)和戴镜年数(r=-0.167,P=0.018)轻度相关,情感维度与戴镜年数轻度相关(r=0.209,P=0.003)。量表总分在不同戴镜年数[(3.60±0.34)年vs.(3.71±0.32)年,P=0.026]、每月戴镜天数[(3.60±0.33)d vs.(3.70±0.33)d,P=0.041]和无/有眼部症状(3.71±0.32 vs.3.60±0.34,P=0.021)的配戴者间差异有统计学意义。软镜配戴者的经济维度得分高于硬镜配戴者(t=2.588,P=0.017)。结论:删去视功能维度、认知维度和条目20后,CLIQ量表的信度和效度较好,戴镜年数越长、每月戴镜天数越多以及无眼部症状的患者得分较高,硬镜配戴者在花费方面的担忧更多。Objective:To develop a Chinese version of the Contact Lens Impact on Quality of Life questionnaire(CLIQ),assess its reliability and validity,and analyze the factors that influence the score.Methods:A Chinese version of CLIQ was developed,including forward and backward translation and a cultural adaptation of the original English CLIQ.Then a cross-sectional investigation was carried out.Two hundred and five patients were selected from the Eye Hospital,Wenzhou Medical Universtity and than evaluated using the Chinese version of CLIQ,20 of them were randomly selected and evaluated by two investigators separately.Questionnaire data were statistically analyzed.Results:A total 201 questionnaires were analyzed.The visual function domain was discarded because of the low response rate(less than 50%).Cronbach'sαcoefficient scale was 0.77,the ocular symptoms domain was 0.68,and the convenience,economy and well-being domains were more than 0.7.The Guttmann Split-half reliability scale was 0.89,and 0.75,0.78,0.65 and 0.93 for the ocular symptoms,convenience,economy and well-being domains,respectively.Cronbach'sαcoefficient and Guttmann Split-half coefficient were both 0.49 for the cognitive domain.Cronbach'sαcoefficient and Guttmann Split-half coefficient increased to 0.68 and 0.73,respectively,after deleting item 20 in the well-being domain,so items 15,16 and 20 were deleted.Scores between the two investigators had a high positive correlation(r=0.87-0.99,P<0.001).The item level content validity index of each item was 0.83-1.00;the average level of the content validity index of the scale was 0.95.Five extracted factors corresponded to each domain by exploratory factor analysis and the cumulative variance contribution rate was 60.43%.The ocular symptoms domain had as light negative correlation with age(r=-0.153,P=0.03)and the number of years the lenses were worn(r=-0.167,P=0.018);the well-being domain was slightly correlated with the number of years the lenses were worn(r=0.209,P=0.003).The total score of the scale was signi

关 键 词：患者报告结局 接触镜配戴者生活质量量表 角膜接触镜 生活质量 信度 效度 

分 类 号：R77[医药卫生—眼科]