磁共振征象与肝癌术后早期复发的相关性分析  

Correlation analysis between MRI signs and early postoperative recurrence of liver cancer

作　　者：王鹏 阳君[2] 赵阳[2] 邓文娟[2] 陆一昕 李印 叶甲舟[3] 罗宁斌[2] Wang Peng;Yang Jun;Zhao Yang;Deng Wenjuan;Lu Yixin;Li Yin;Ye Jiazhou;Luo Ningbin(Department of Radiology,Wuhan No.1 Hospital,Wuhan 430022,China;Medical Imaging Center,Guangxi Medical University Affiliated Tumor Hospital,Nanning 530021,China;Hepatobiliary Surgery,Guangxi Medical University Affiliated Tumor Hospital,Nanning 530021,China)

机构地区：[1]湖北省武汉市第一医院放射科,武汉430022 [2]广西医科大学附属肿瘤医院医学影像中心,南宁530021 [3]广西医科大学附属肿瘤医院肝胆外科,南宁530021

出　　处：《广西医科大学学报》2020年第3期487-491,共5页Journal of Guangxi Medical University

基　　金：国家自然科学基金青年科学基金项目(No.81803007);广西壮族自治区卫生厅科研课题资助项目(No.Z2016484)。

摘　　要：目的:探讨术前磁共振征象与肝癌微血管侵犯(MVI)及术后复发的相关性。方法:收集2013年1月至2016年7月收治的肝癌患者术前磁共振及临床病理资料,并进行术后两年以上随访。以COX回归模型对肝癌患者术后复发进行单因素及多因素分析。结果:共计收集到肝癌患者82例,早期复发19例(23.2%)。COX回归模型单因素分析结果显示,肿瘤包膜、结节类型以及MVI与肝癌术后早期复发相关(均P<0.05);COX回归模型多因素分析结果显示,肿瘤包膜(HR=2.006,P=0.026)、MVI(HR=4.267,P=0.011)是肝癌术后早期复发的危险因素。结论:肝癌术前磁共振征象与其术后早期复发具有一定的相关性,对临床具有重要的预测价值。Objective:To investigate the correlation between preoperative MRI signs,microvascular invasion(MVI)and postoperative recurrence of liver cancer.Methods:The preoperative MRI and clinicopathological data of liver cancer patients admitted from January 2013 to July 2016 were retrospectively analyzed and followed up for more than 2 years after surgery.The COX analysis proportional model was used to perform univariate and multivariate analysis of postoperative recurrence of liver cancer.Results:A total of 82 cases with liver cancer were collected,including 19(23.2%)patients with early postoperative recurrence.COX risk ratio model univariate analysis showed that tumor capsule,nodule type and MVI were related to early postoperative recurrence of liver cancer(all P<0.05).COX multivariate analysis showed that tumor capsule(HR=2.006,P=0.026)and MVI(HR=4.267,P=0.011)are were risk factors for early recurrence of liver cancer.Conclusion:The preoperative MRI signs of liver cancer have certain correlation with early postoperative recurrence,and have important predictive value for the clinical treatment.

关 键 词：肝癌 微血管侵犯 早期复发 磁共振 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]