雷替曲塞TACE治疗胃癌术后肝转移患者的临床疗效  

Clinical efficacy of raltitrexed TACE in the treatment of postoperative liver metastases from patients with gastric cancer

作　　者：刘爱俊 Liu Aijun(Department of Tumor Blood Medicine,First People's Hospital of Pingyuan County,Dezhou City,Shandong Province,Dezhou,Shandong,253100,China)

机构地区：[1]山东省德州市平原县第一人民医院肿瘤血液内科,山东德州253100

出　　处：《当代医学》2020年第13期63-65,共3页Contemporary Medicine

摘　　要：目的研究雷替曲塞肝动脉化疗栓塞(TACE)治疗胃癌术后肝转移患者的有效性。方法选取2017年5月至2018年8月本院收治的44例胃癌术后肝脏转移患者,随机分为观察组和对照组,各22例。观察组实施雷替曲塞+吡柔比星+奥沙利铂行TACE治疗,对照组实施5-氟尿嘧啶+吡柔比星行TACE治疗,比较两组治疗效果及不良反应。结果观察组客观有效率和疾病控制率均高于对照组(P<0.05),两组不良反应比较差异无统计学意义。结论应用雷替曲塞对胃癌术后肝脏转移患者进行治疗,有效性强,安全性高。Objective To study the efficacy of raltitrexed hepatic arterial chemoembolization(TACE)in the treatment of patients with liver metastases after gastric cancer.Methods From May 2017 to August 2018,44 patients with liver metastasis after gastric cancer operation were randomly divided into observation group and control group,with 22 cases in each group.The observation group received TACE treatment with letetrexed+pirarubicin+oxaliplatin,and the control group received TACE treatment with 5-fluorouracil+pirarubicin.The therapeutic effect and adverse reactions were compared between the two groups.The therapeutic effects and adverse reactions were compared between the two groups.Results The objective efficiency and disease control rate of the observation group were higher than the control group(P<0.05).There was no significant difference in adverse reactions between the two groups.Conclusion The application of letetrexed in the treatment of liver metastasis after gastric cancer surgery has strong efficacy and high safety..

关 键 词：雷替曲塞 胃癌 肝转移 奥沙利铂 

分 类 号：R735.2[医药卫生—肿瘤]