RS4型抗性淀粉对大鼠血清免疫球蛋白含量、免疫器官发育和盲肠黏膜形态结构的影响  

Effects of Resistant Starch Type 4 on Body Immunity and Cecal Morphology of Growing Rats

作　　者：李凌岩[1] 高伟星 杨敏娜 胡杰[1] 张爱忠[1] 曲永利[1] Li Lingyan;Gao Weixing;Yang Minna;Hu Jie;Zhang Aizhong;Qu Yongli(College of Animal Science and Veterinary Medicine,Heilongjiang Bayi Agricultural University,Daqing 163319)

机构地区：[1]黑龙江八一农垦大学动物科技学院,大庆163319

出　　处：《黑龙江八一农垦大学学报》2020年第2期32-36,67,共6页journal of heilongjiang bayi agricultural university

基　　金：黑龙江八一农垦大学学成、引进科研启动项目(XYB2015-06);黑龙江八一农垦大学三横三纵支持计划(TDJH201805)。

摘　　要：试验旨在研究饲粮中添加不同浓度RS4型抗性淀粉对生长大鼠血清免疫球蛋白含量、免疫器官发育和盲肠黏膜形态结构的影响。试验选取SD大鼠36只,平均分为4组(对照组和3个处理组)。对照组大鼠不含抗性淀粉的基础饲粮,处理组分别饲喂含量为5%、10%、15%的RS4型抗性淀粉饲粮。饲喂40 d后将大鼠处死采样。试验结果显示:与对照组相比,15%RS4型抗性淀粉组大鼠血清中IgA和IgM含量显著增加(P<0.05);脾脏指数也显著提高(P<0.05)。15%RS4型抗性淀粉组大鼠的盲肠绒毛高度显著降低(P<0.05)。10%RS4型抗性淀粉组大鼠的绒毛高度和隐窝深度的比值显著高于其他3组(P<0.05)。由此得出,饲粮中添加RS4型抗性淀粉对于提高机体的免疫功能具有积极作用。但是长时间摄入高浓度的抗性淀粉会对盲肠黏膜上皮形态结构造成损伤。饲粮中添加10%RS4型抗性淀粉可以在提高大鼠机体免疫力,促进盲肠发育这两方面发挥最佳效果。The study was carried out to evaluate the effects of dietary resistant starch type 4(RS4)on serum immunoglobulin content,immune organ development and cecal morphology of growing rats.Thirty-six SD rats were divided into four groups(control group and 3 treatment groups).Rats of control group were fed diet without RS4,while rats of treatment groups were fed with 5%,10%and 15%dietary RS4 respectively.Samples of rats were collected after feeding for 40 days.The results revealed that compared with the control group,rats fed with 15%RS4 had higher serum IgA、IgM levels and spleen index(P<0.05).The villus height was significantly decreased for the rats fed with 15%RS4 compared with the control group.Rats fed with 10%RS4 had higher villus/crypt ratio than the other three groups(P<0.05).These findings suggested that dietary RS4 could improve the immunity of the body.However,long-term intake of high concentration of RS4 could damage the cecal morphology.Rats fed with 10%RS4 had the most advantageous effects immunity of the body and the development of cecum.

关 键 词：抗性淀粉 免疫 盲肠 黏膜 大鼠 

分 类 号：TS231[轻工技术与工程—粮食、油脂及植物蛋白工程]