1例阴茎丛状神经鞘瘤的临床病理特征及文献复习  

Clinical and pathological features of plexiform schwannoma of the penis: A case report

作　　者：赵涓涓[1] 张弘[1] 雷露[1] 吕思佳 ZHAO Juanjuan;ZHANG Hong;LEI Lu;LV Sijia(Department of Pathology,Ezhou Central Hospital,Ezhou Hubei 436000,China)

机构地区：[1]鄂州市中心医院病理科,湖北鄂州436000

出　　处：《临床与病理杂志》2020年第4期1063-1069,共7页Journal of Clinical and Pathological Research

摘　　要：采用光镜及免疫组织化学(immunohistochemistry,IHC)等方法对1例阴茎丛状神经鞘瘤进行临床、病理回顾性分析。患者因阴茎无痛性肿块入院,镜下见肿瘤由纤维结缔组织间隔为多结节,结节内由束状区(Antoni A区)的施万细胞构成,可见栅栏状结构,周围可见少许黏液样间质。瘤细胞表达Vimentin,S-100,不表达胶质纤维酸性蛋白(glial fibrillary acidic portein,GFAP),周围黏液样间质表达CD34。阴茎丛状神经鞘瘤少见,临床诊断困难,明确诊断需要病理广泛取材及IHC检测。治疗以手术切除为主,预后好。A case of plexiform schwannoma of the penis was retrospectively analyzed by light microscopy and immunohistochemistry(IHC). Th e patient was hospitalized for painless mass of the penis. Microscopically, the tumor was composed of multiple nodules with fibrous connective tissue septum. Th e nodules were composed of Schwann cells in the bundle area(Antoni A), with palisade structure and a litt le mucoid stroma around them. Th e tumor cells expressed Vimentin and S-100, but not glial fibrillary acidic portein(GFAP). CD34 was expressed in the surrounding mucoid stroma. Plexiform schwannoma of the penis is rare and difficult to diagnose clinically. A definite diagnosis requires extensive pathological sampling and IHC detection. Surgical resection is the main treatment with good prognosis.

关 键 词：阴茎 丛状神经鞘瘤 泌尿生殖系肿瘤 

分 类 号：R737.27[医药卫生—肿瘤]