Isaacs综合征5例报告并文献回顾  

Cases report and literature review of Isaacs syndrome

作　　者：陈万红 宋文锋[2] CHEN Wan-hong;SONG Wen-feng(Department of Neurology,Xi’an XD Group Hospital,Xi’an 710077,China)

机构地区：[1]西电集团医院神经内科,710077 [2]西安交通大学第一附属医院神经内科

出　　处：《临床神经病学杂志》2020年第2期118-122,共5页Journal of Clinical Neurology

摘　　要：目的探讨Isaacs综合征潜在的发病机制、临床表现、诊断及治疗。方法回顾性分析2017年3月至2019年3月收治的5例Isaacs综合征患者临床资料,并进行相关文献复习。结果5例患者均为男性,主要表现为肌肉颤搐、痉挛、多汗,4例予以卡马西平和泼尼松口服治疗,效果良好。结论Isaacs综合征临床罕见,对症治疗和免疫治疗不可或缺。Objective To explore the potential pathogenesis,clinical presentation,diagnosis and management of Isaacs syndrome.Methods The clinical data of five cases of Isaacs syndrome between March 2017 and March 2019 were analyzed retrospectively,and related literatures were reviewed.Results All five patients with Isaacs syndrome were males,and complained of muscle cramping,myokymia and hyperhidrosis.Four of them were treated with carbamazepine and prednisone,and got good responses.Conclusion Isaacs syndrome is a rare disorder in which symptomatic and immunomodulating therapy may play integral roles.

关 键 词：ISAACS综合征 肌肉颤搐 卡马西平 免疫治疗 

分 类 号：R746[医药卫生—神经病学与精神病学]