进展期直肠癌新辅助放化疗研究进展  

Research progress in neoadjuvant chemoradiotherapy for advanced rectal cancer

作　　者：高倩闽 陈昕涛 姚厚山 胡志前 Gao Qianmin;Chen Xintao;Yao Houshan;Hu Zhiqian(Team 11,Basic Medical College of the Second Military Medical University,Shanghai 200433,China;Department of General Surgery,Changzheng Hospital,Shanghai 200003,China)

机构地区：[1]第二军医大学基础医学院学员11队,200433 [2]上海长征医院普外一科,200003

出　　处：《中华结直肠疾病电子杂志》2020年第2期188-195,共8页Chinese Journal of Colorectal Diseases(Electronic Edition)

摘　　要：我国结直肠癌发病率和死亡率居高不下,直肠癌的发病率与术后局部复发率(LRR)通常高于结肠癌,且手术难度高。目前为了防止直肠癌的局部复发大多采取多学科方法医治。新辅助放化疗(nCRT)作为一种发展中的多学科方法,可提高治愈率又可维持器官功能,在直肠癌治疗中起着至关重要的作用。本综述旨在阐明nCRT的现状与未来的改进方向。The incidence and death rate of colorectal cancer are very high in China.The incidence and local recurrence rate of rectal cancer are usually higher than that of colon cancer.And the operation is difficult.At present,to prevent the local recurrence of rectal cancer,multidisciplinary treatment is widely used.Neoadjuvant chemoradiotherapy(nCRT),as a developing multidisciplinary method,can not only guarantee the curative effect but also maintain the organ function,and plays a crucial role in the treatment of rectal cancer.The purpose of this review is to clarify the current situation and future improvement direction of nCRT.

关 键 词：直肠肿瘤 进展期直肠癌 新辅助化疗 新辅助放疗 新辅助放化疗 局部复发率 

分 类 号：R735.37[医药卫生—肿瘤]