1型神经纤维瘤病切除术中出血量相关因素分析  

Analysis of Related Factors of Intraoperative Blood Loss in Neurofibromatosis Type 1

作　　者：李娜[1] 刘苗苗 刘林嶓[1] 翟晓梅[1] LI Na;LIU Miao-miao;LIU Lin-bo;ZHAI Xiao-mei(Department of Plastic Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan,China)

机构地区：[1]郑州大学第一附属医院整形外科,河南郑州450052

出　　处：《中国美容医学》2020年第4期87-90,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨各相关因素对1型神经纤维瘤病切除术中出血量的影响。方法:回顾性分析2011年1月-2018年12月笔者医院整形外科收治的60例1型神经纤维瘤病切除术中出血量与各因素的相关性。结果:单因素分析中,性别、年龄、是否多发、是否有家族史、是否物理止血、切除方式这些因素差异无统计学意义(P>0.05)。而瘤体的主要位置、瘤体截面积、手术时间、是否侵及肌层、术中输液量等因素差异有统计学意义(P<0.05)。对术中出血量、住院时间及住院花费行相关性分析,可对住院时间及住院花费行预估计。对单因素分析中有意义的指标进行Logistic回归分析,可得瘤体截面积和是否侵及肌层是影响术中出血量的独立危险因素。结论:瘤体截面积和瘤体侵及层次是影响术中出血量的重要因素。术前可通过用影像学检查明确侵及层次,计算瘤体截面积预估出血量,必要时备血,提高手术安全性。Objective To investigate the influence of various related factors on the amount of bleeding in the treatment of neurofibromatosis type 1(NF1).Methods Retrospectively analyzed the correlation between the amount of bleeding and factors in 60 cases of NF1 resection in our hospital from January 2011 to December 2018.Results In the univariate analysis,gender,age,multiple occurrence,family history,physical hemostasis,and resection methods were not statistically significant(P>0.05).While the main location of the tumor,the cross-sectional area of the tumor,the operation time,whether it invaded the muscle layer,and the amount of intraoperative fluid infusion were statistically significant(P<0.05).The correlation analysis of intraoperative blood loss,length of stay and cost of hospitalization can be used to estimate the length of stay and cost of hospitalization.Logistic regression analysis of meaningful indicators in univariate analysis shows that the tumor cross-sectional area and whether it invades the muscle layer are independent risk factors that affect the intraoperative blood loss.Conclusion The cross-sectional area of the tumor and the invasion level of the tumor are important factors influencing the amount of intraoperative blood loss.Preoperative imaging examination can be used to determine invasion level,calculate tumor cross-sectional area to estimate blood loss,and prepare blood when necessary to improve surgical safety.

关 键 词：1型神经纤维瘤病 术中出血量 瘤体截面积 瘤体侵及层次 手术切除 

分 类 号：R622[医药卫生—整形外科]