免疫组化在肺小细胞癌活检诊断中的作用  

The Role of Immunohistochemistry in the Diagnosis of Small Cell Lung Cancer by Biopsy

作　　者：陈鹤 CHEN He(Liaoyang Central Hospital,Liaoyang 111000,China)

机构地区：[1]辽宁省辽阳市中心医院,辽宁辽阳111000

出　　处：《中国医药指南》2020年第12期173-174,共2页Guide of China Medicine

摘　　要：目的分析免疫组化在肺小细胞癌活检诊断中的作用。方法随机抽取我院2016年~2017年收治的50例肺穿刺与支气管镜活检患者作为本次报告的研究对象,进行Syn、ki67、CgA、34βE12、P63、CK5/6、LCA免疫组化诊断。结果全体患者均确诊肺癌,倾向肺小细胞癌活检标本通过免疫组化的证实,3例非何杰金氏淋巴瘤、9例低分化鳞癌、38例小细胞肺癌。结论免疫组化CgA、CK5/6、TTF-1以及Syn是肺小细胞癌诊断的可靠性指标,四种指标的联合使用会充分提高诊断准确率,在肺小细胞癌鉴别诊断以及诊断中有着十分重要的作用。Objective To analyze the role of immunohistochemistry in the diagnosis of small cell lung cancer.Methods 50 patients with lung biopsy and bronchoscopy from 2016 to 2017 in our hospital were randomly selected as the research objects of this report.Syn,Ki67,CGA,34βE12,p63,CK5/6,LCA immunohistochemical diagnosis was carried out.Results All the patients were diagnosed with lung cancer.Three cases of non Hodgkin's lymphoma,9 cases of poorly differentiated squamous cell carcinoma and 38 cases of small cell lung cancer were confirmed by immunohistochemistry.Conclusion CGA,CK5/6,TTF-1 and syn are reliable indexes in the diagnosis of small cell lung cancer.The combined use of these four indexes will fully improve the accuracy of diagnosis and play an important role in the differential diagnosis and diagnosis of small cell lung cancer.

关 键 词：免疫组化 肺小细胞癌 活检诊断 非何杰金氏淋巴瘤 低分化鳞癌 

分 类 号：R734.2[医药卫生—肿瘤]