北海市113例皮肤基底细胞癌临床特点分析  

Analysis of clinical characteristics of 113 cases of basal cell carcinoma of skin in Beihai city

作　　者：韦海鹏[1] 詹松[1] 朱庆安 冯仙 陈贞娟 杨晓洁 张棋麟 WEI Haipeng;ZHAN Song;ZHU Qing'an;FENG Xian;CHEN Zhenjuan;YANG Xiaojie;ZHANG Qilin(Department of Dermatology&STD,Beihai People's Hospital,Beihai 536000,Guangxi,China;Faculty of Life Science and Technology,Kunming University of Science and Technology,Kunming 650500,Yunnan,China)

机构地区：[1]广西北海市人民医院皮肤性病科,广西北海536000 [2]昆明理工大学生命科学与技术学院,云南昆明650500

出　　处：《右江医学》2020年第4期272-275,共4页Chinese Youjiang Medical Journal

基　　金：北海市科技计划项目(北科合201884029)。

摘　　要：目的了解北海地区人群基底细胞癌临床特征。方法回顾性分析2013年8月1日至2019年8月1日北海市人民医院皮肤科诊治的113例经病理活检确诊为皮肤基底细胞癌病例临床资料和病理资料。记录患者的性别、年龄、发病部位、病程、肿瘤皮损大小、病理类型等基础资料,比较分析不同性别人群间的上述临床特征。结果本组基底细胞癌患者好发于60岁以上的老年人,占73.45%。其中男66例,平均(68.3±17.2)岁,女47例,平均(64.5±16.1)岁,男性和女性年龄比较差异无统计学意义(t=1.189,P=0.237)。113例患者中单发患者107例(94.69%),多发患者6例(5.31%),皮损数均为2个,均分布于面颊部。发病部位以面部、鼻部及头部多见,占84.95%,不同性别的发病部位构成比较差异无统计学意义(χ^2=5.168,v=5,P=0.396)。66例男性患者,平均病程(6.94±6.32)年,47例女性患者,平均病程(7.88±7.21)年,两组比较差异无统计学意义(t=0.735,P=0.464)。113例患者合计皮损数125个,肿瘤皮损面积中位数为0.91 cm^2。66例男性患者肿瘤皮损面积中位数为0.93 cm^2,47例女性患者肿瘤皮损面积中位数为0.90 cm^2,两组比较差异无统计学意义(Z=0.886,P=0.538)。113例患者中,结节型91例,男性54例(59.34%),女性37例(40.66%),非结节型22例,男性12例(54.55%),女性10例(45.45%),两组比较差异无统计学意义(χ^2=0.168,P=0.682)。结论北海市基底细胞癌好发于老年人,多见于男性,其病程长,主要分布于头面部,临床及病理类型以结节型为主。在年龄、发病部位、病程、病理类型及肿瘤皮损面积等方面,未见与性别有关联。Objective To understand the clinical characteristics of basal cell carcinoma(BCC) in Beihai city.Methods From August 1,2013 to August 1,2019,the clinical data of 113 BCC cases of skin diagnosed and treated by dermatology department of Beihai People’s Hospital were analyzed retrospectively.The basic data of patients included sex,age,location,course of disease,size of tumor lesions and pathological types were recorded,and the above clinical characteristics of different groups were compared and analyzed.Results The incidence of BCC in this group was 73.45% in the elderly over 60 years old.Among them,66 cases were males,and average age was(68.3±17.2) years,47 cases were females,and average age was(64.5±16.1) years,difference of age between males and females was not statistically significant(t=1.189,P=0.237).Of the 113 patients,there were 107 single BCC patients(94.69%) and 6 multiple BCC patients(5.31%),the number of lesions was 2,all of which were distributed on the cheek.In this group,the main sites of the disease were face,nose and head,accounting for 84.95%,and there was no statistically significant difference in the composition of the disease sites between different genders(χ^2=5.168,v=5,P=0.396).The average course of disease was(6.94±6.32) years in 66 men and(7.88±7.21) years in 47 women,and difference was not statistically significant(t=0.735,P=0.464).Of the 113 patients, the total number of skin lesions was 125,and the median area of tumor skin lesions was 0.91 cm^2.Among the 113 patients,the median area of tumor lesions in 66 males was 0.93 cm^2,and that in 47 females was 0.90 cm^2,there was no significant difference between the two groups(Z=0.886,P=0.538).Among 113 patients,91 were nodular type with 54 males(59.34%) and 37 females(40.66%),22 were non nodular type with 12 male(54.55%) and 10 female(45.45%),and difference was not statistically significant(χ^2=0.168,P=0.682).Conclusion In Beihai city,BCC is more common in older men.It has a long course and is mainly distributed in head and face,and the

关 键 词：基底细胞癌 临床特点 组织病理 性别 

分 类 号：R739.5[医药卫生—肿瘤]