双相障碍和精神分裂症患者的语音情绪识别  

Difference of speech emotion perception in patients with bipolar disorder and schizophrenia

作　　者：杜霞 范宏振[2] 王云辉[2] 张洁[2] 朱小林[2] 赵艳丽[2] 谭淑平[2] DU Xia;FAN Hongzhen;WANG Yunhui;ZHANG Jie;ZHU Xiaolin;ZHAO Yanli;TAN Shuping(Peking University Sixth Hospital,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100083,China;Beijing Huilongguan Hospital,Peking University Huilongguan Clinical Medical School,Beijing 100096,China)

机构地区：[1]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100083 [2]北京回龙观医院北京大学回龙观临床医学院,北京100096

出　　处：《中国心理卫生杂志》2020年第6期487-492,共6页Chinese Mental Health Journal

基　　金：北京市自然科学基金(7162087);首都临床特色应用研究(Z141107002514016)。

摘　　要：目的:比较双相障碍和精神分裂症患者的语音情绪识别的差异。方法:符合美国精神障碍诊断与统计手册第四版诊断标准的双相障碍患者和精神分裂症患者各60例,性别、年龄和受教育年限匹配的正常对照60例。使用阳性和阴性症状量表、杨氏躁狂量表和24项汉密顿抑郁量表评估患者临床症状,使用42段标准化语音情绪评价范式测试所有受试者的语音情绪识别能力。结果:双相障碍和精神分裂症的患者的愤怒、平静、悲伤及总体语音情绪类别得分均低于正常对照(P<0.05),其中精神分裂症对厌恶;(2.1±1.7)vs.(3.1±1.7)vs.(3.1±1.6);P<0.05]、惊奇;(2.7±1.7)vs.(3.8±1.6)vs.(3.9±1.7);P<0.05]两种语音情绪的类别得分,及对愤怒;(58.4±22.1)vs.(71.4±17.1)vs.(71.1±14.5);P<0.05]情绪的强度得分均低于双相障碍和正常对照。结论:本研究提示双相障碍和精神分裂症的患者均存在语音情绪识别障碍,精神分裂症患者对厌恶、惊奇两种语音情绪的识别能力弱于双相障碍患者。Objective:To explore the characteristics of speech emotion perception between patients with bipolar disorder and schizophrenia.Methods:Totally 60 patients with bipolar disorder and 60 patients with schizophrenia who met the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition,60 normal controls matched for gender,age and education years were recruited.Patients underwent clinical assessments with the Positive and Negative Symptom Scale,Young Mania Rating Scale and 24-item Hamilton Depression Scale.All subjects were received a standardized voice emotional perception test with a set of 42 phonetic clip.Results:The classification scores of anger,calmness,sadness and general voice emotion in bipolar disorder and schizophrenia were lower than those in normal control(P<0.05).Patients with schizophrenia got lower voice emotional classification scores in disgust[(2.1±1.7)vs.(3.1±1.7)vs.(3.1±1.6);P<0.05)],surprise[(2.7±1.7)vs.(3.8±1.6)vs.(3.9±1.7);P<0.05)],and lower intensity precepted in anger[(58.4±22.1)vs.(71.4±17.1)vs.(71.1±14.5);P<0.05)]than those with bipolar disorder and normal control.Conclusion:There may be deficits of voice emotion perception in patients with bipolar disorder and schizophrenia.The perception ability of disgust and surprise in patients with schizophrenia may be weaker than that in bipolar disorder.

关 键 词：双相障碍 精神分裂症 语音情绪识别 

分 类 号：R749.1[医药卫生—神经病学与精神病学] R749.3[医药卫生—临床医学]