超声引导下经皮微波消融治疗肝尾状叶原发性大肝癌(附13例报道)  

Ultrasound-guided percutaneous microwave ablation in the treatment of large hepatocellular carcinoma in the cauda lobe(a report of 13 cases)

作　　者：崔丹[1] 丁敏[1] 李伟建 池嘉昌[1] 李萍[1] 翟博[1] CUI Dan;DING Min;LI Wei-jian;CHI Jia-chang;LI Ping;ZHAI Bo(Department of Interventional Oncology,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China)

机构地区：[1]上海交通大学医学院附属仁济医院肿瘤介入科,200127

出　　处：《肝脏》2020年第4期355-358,共4页Chinese Hepatology

基　　金：国家科技重大专项课题-艾滋病和病毒性肝炎等重大传染病防治(2017ZX10203206-006-002)。

摘　　要：目的评估微波消融治疗肝尾状叶大肿瘤的安全性、有效性。方法总结2011年12月至2018年9月上海市仁济医院13例尾状叶原发性大肝癌患者微波消融治疗的临床资料,探讨微波消融治疗尾状叶大肝癌的完全消融率、并发症以及患者预后情况。结果13例患者均成功消融。初次完全消融率10例,总消融12例;1、2,3年总体生存分别为11例、10例和6例;2例发生消融相关性梗阻性黄疸,经治疗后恢复正常,未见相关手术死亡。结论对于高危部位的尾状叶肝脏大肿瘤,微波消融治疗安全、有效、可行,可作为不可切除患者有潜力的候选或替代。Objective To evaluate the safety and efficacy of microwave ablation for large primary liver tumor in the caudate lobe.Methods The clinical data of 13 patients with large primary liver tumors in the caudate lobe treated by microwave ablation in our hospital from December 2011 to September 2018 were collected.And the complete ablation rate,complications and prognosis of these patients were analyzed.Results All the 13 patients were ablated successfully.The complete ablation rate was 76.9%for the first ablation and the overall ablation rate was 92.3%.The 1-year,2-year and 3-year overall survival rates were 84.5%,74.0%and 49.4%,respectively.Ablation-related obstructive jaundice occurred in 2 patients,which subsided after treatment,and no death was observed.Conclusion For large tumors in the caudate lobe of the liver at high risk sites,microwave ablation is safe,effective and feasible.And it can be used as a potential treatment of non-resectable liver tumors.

关 键 词：肝细胞癌 尾状叶 微波消融 

分 类 号：R73[医药卫生—肿瘤]