贲门失驰缓症的诊断与治疗的进展及未来前景  

Progress of diagnosis and treatment of achalasia and its future prospects

作　　者：杨烁[1] 徐洪雨[1] YANG Shuo;XU Hongyu(Department of Gastroenterology,the First Clinical Hospital Affiliated to Harbin Medical University,Harbin 150000,China)

机构地区：[1]哈尔滨医科大学附属第一临床医院消化内科,黑龙江哈尔滨150000

出　　处：《胃肠病学和肝病学杂志》2020年第4期462-465,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：贲门失弛缓症(achalasia,AC)是一种慢性特发性的食管运动障碍性疾病,目前病因及发病机制尚不明确,该病以食管体部正常蠕动消失及吞咽时下食管括约肌(lower esophageal sphincter,LES)松弛不良为特征。高分辨食管测压(high-resolution esophageal manometry,HRM)的出现已成为诊断AC的金标准。治疗目的是通过给予能够诱导LES松弛的药物治疗、内镜下治疗、外科手术治疗来减轻患者症状并改善他们的生活质量。本文拟对AC的诊断、治疗的进展及未来前景及不同治疗方法疗效对比作一概述。Achalasia(AC)is a chronic idiopathic dyskinesia esophageal disease,etiology and pathogenesis are not clear.It is characterized by the disappearance of normal peristalsis of the esophageal body and the poor relaxation of the lower esophageal sphincter(LES)during swallowing.The emergence of high-resolution esophageal manometry(HRM)has become the gold standard for the diagnosis of AC.The goal of treatment is to reduce the symptoms of patients and improve their quality of life by giving medications that can relax LES,including drug therapy,endoscopic therapy and surgery treatment.The diagnosis of AC,the progress of treatment,the future prospects and the comparison of the efficacy of different treatments were reviewed in this article.

关 键 词：贲门失弛缓症 经口内镜下肌切开术 诊断 治疗 

分 类 号：R571[医药卫生—消化系统]