PSMA配体PET显像在非前列腺肿瘤诊疗中的应用  

Application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors

作　　者：王观筠 于鹏[1] 宁静[1] 徐白萱[1] Wang Guanyun;Yu Peng;Ning Jing;Xu Baixuan(Department of Nuclear Medicine,Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院核医学科,北京100853

出　　处：《中华核医学与分子影像杂志》2020年第4期243-246,共4页Chinese Journal of Nuclear Medicine and Molecular Imaging

基　　金：国家自然科学基金(81571715)。

摘　　要：前列腺特异膜抗原(PSMA)是前列腺癌分子影像学研究的热点.但PSMA也可在非前列腺的生理组织及其他多种良恶性疾病中表达,特别是在肿瘤相关的新生血管内皮细胞中高表达.相关临床研究已表明PSMA配体PET显像在指导非前列腺癌的其他恶性肿瘤分期中具有应用价值.该文对PSMA配体PET显像在非前列腺肿瘤诊断和治疗中的应用进行综述.Prostate specific membrane antigen(PSMA)is a hot topic in molecular imaging research of prostate cancer.However,non-prostate related PSMA can also be expressed in physiological tissues and different benign and malignant diseases,especially in tumor-associated endovascular endothelial cells.Related clinical studies have demonstrated the staging potential of PSMA ligands PET imaging in non-prostate tumors.This article summarizes the application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors.

关 键 词：前列腺特异膜抗原 正电子发射断层显像术 发展趋势 

分 类 号：R73[医药卫生—肿瘤]