MODY基因多态性与早发2型糖尿病相关性研究进展  

Research Progress of Correlation between MODY Gene Polymorphism and Early-onset Type 2 Diabetes

作　　者：陈梦蝶 蔡宁宇 叶迅[2] 冯萍 刘俏 CHEN Meng-die;CAI Ning-yu;YE Xun;FENG Ping;LIU Qiao(Taizhou Central Hospital(Affiliated Hospital of Taizhou University),Taizhou,Zhejiang Province,318000 China;Hangzhou Traditional Chinese Medicine Hospital,Hangzhou,Zhejiang Province,310007 China)

机构地区：[1]台州市中心医院(台州学院附属医院),浙江台州318000 [2]杭州市中医院,浙江杭州310007

出　　处：《糖尿病新世界》2020年第3期195-196,共2页Diabetes New World Magazine

摘　　要：早发2型糖尿病(T2DM)不仅严重威胁着患者的身心健康,也给社会带来沉重的经济负担,而遗传因素在早发T2DM发病中起着重要作用。青少年发病的成人型糖尿病(MODY)发病相关基因的单核苷酸多态性在早发T2DM患者中导致其遗传易感性增加的现象逐渐引起重视。该文对MODY基因与早发T2DM的相关性研究进展进行文献综述。Early-onset type 2 diabetes(T2DM)not only seriously threatens the physical and mental health of patients,but also brings a heavy economic burden on society.Genetic factors play an important role in the onset of early-onset T2DM.Single-nucleotide polymorphisms in adolescent-onset adult-onset diabetes(MODY)-associated genes have led to increased genetic susceptibility in patients with early-onset T2DM.This article reviews the research progress of the correlation between MODY gene and early-onset T2DM.

关 键 词：MODY 基因 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]