COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report  

作　　者：Mian Peng Di Ren Xue-Yan Liu Jin-Xiu Li Rong-Lin Chen Bao-Jun Yu Yong-Feng Liu Xi Meng Yan-Si Lyu 

机构地区：[1]Department of Intensive Care Unit,the Third Affiliated Hospital of Shenzhen University,Shenzhen 518001,Guangdong Province,China [2]Department of Intensive Care Unit,the Second People’s Hospital of Shenzhen,Shenzhen 518001,Guangdong Province,China [3]Department of Intensive Care Unit,Shenzhen People's Hospital,First Affiliated Hospital of Southern University of Science and Technology,the Second Affiliated Hospital of Jinan University,Shenzhen 518020,Guangdong Province,China [4]Department of Intensive Care Unit,the Third People’s Hospital of Shenzhen,Shenzhen 518001,Guangdong Province,China [5]Department of Intensive Care Unit,Shenzhen Longgang Central Hospital,Shenzhen 518001,Guangdong Province,China [6]Department of Intensive Care Unit,Shenzhen Baoan District People’s Hospital,Shenzhen 518001,Guangdong Province,China [7]Department of Dermatology,Shenzhen University General Hospital,Shenzhen 518067,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2020年第9期1705-1712,共8页世界临床病例杂志

基　　金：We acknowledge the writing guidance provided by Prof.Kun-Mei Ji and the training camp for medical research held by Shenzhen Medical Association and Huada.We are grateful to the physicians and nurses at the Third People’s Hospital of Shenzhen who participated in clinical examinations and sample collection.

摘　　要：BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has become an immense public health burden,first in China and subsequently worldwide.Developing effective control measures for COVID-19,especially measures that can halt the worsening of severe cases to a critical status is of urgent importance.CASE SUMMARY A 52-year-old woman presented with a high fever(38.8°C),chills,dizziness,and weakness.Epidemiologically,she had not been to Wuhan where COVID-19 emerged and did not have a family history of a disease cluster.A blood test yielded a white blood cell count of 4.41×109/L(60.6±2.67%neutrophils and 30.4±1.34%lymphocytes).Chest imaging revealed bilateral ground-glass lung changes.Based on a positive nasopharyngeal swab nucleic acid test result and clinical characteristics,the patient was diagnosed with COVID-19.Following treatment with early non-invasive ventilation and a bundle pharmacotherapy,she recovered with a good outcome.CONCLUSION Early non-invasive ventilation with a bundle pharmacotherapy may be an effective treatment regimen for the broader population of patients with COVID-19.

关 键 词：COVID-19 NON-INVASIVE ventilation BUNDLE PHARMACOTHERAPY Case report PNEUMONIA CORONAVIRUS 

分 类 号：R563.1[医药卫生—呼吸系统]