保守治疗与支气管动脉栓塞治疗肺癌大咯血的临床疗效比较  

Comparison of the clinical effect of conservative treatment and bronchial artery embolization in the treatment of massive hemoptysis of lung cancer

作　　者：甫拉提·吐尼牙孜[1] 阿美娜·艾合买提[1] 韩峰[1] FULATI·tuniyazi;AMEINA·aihemaiti;HAN Feng(Department of Emergency,Affiliated Cancer Hospital of Xinjiang Medical University,Urumqi Xinjiang 830011,China)

机构地区：[1]新疆医科大学附属肿瘤医院急诊科,新疆乌鲁木齐830011

出　　处：《临床和实验医学杂志》2020年第8期873-875,共3页Journal of Clinical and Experimental Medicine

基　　金：新疆科学研究与发展计划项目(编号:201706A82)。

摘　　要：目的 比较保守治疗与支气管动脉栓塞治疗肺癌大咯血的临床疗效。方法 回顾性分析2014年1月至2019年1月新疆医科大学附属肿瘤医院收治的189例肺癌大咯血患者的病例资料,按照治疗方法不同将患者分为观察组(n=99)和对照组(n=90),观察组患者采用支气管动脉栓塞治疗,对照组患者采用保守治疗,比较两组患者治疗前后凝血指标、咯血量以及临床疗效。结果 观察组患者治疗后凝血酶原时间、纤维蛋白原分别为(15. 79±2. 33) s、(1. 18±0. 31) g/L,显著优于对照组的(13. 51±1. 44) s、(2. 56±0. 44) g/L,差异有统计学意义(P <0. 05);治疗后,观察组患者治疗后3 d、5 d、7 d咯血量分别为(102. 27±14. 21) ml、(74. 29±6. 31) ml、(22. 17±2. 45) ml,明显低于对照组(178. 25±16. 83 ml、114. 31±10. 24 ml、67. 42±5. 73 ml),差异有统计学意义(P <0. 05)。观察组的治疗总有效率(90. 9%)明显高于对照组(61. 1%),差异有统计学意义(χ2=14. 624,P <0. 05)。结论 与保守治疗相比,支气管动脉栓塞治疗肺癌大咯血能更有效地改善患者的凝血指标,减少咯血量,疗效可靠,值得临床借鉴。Objective To compare the clinical effect of conservative treatment and bronchial artery embolization in the treatment of massive hemoptysis of lung cancer.Methods The data of 189 patients with massive hemoptysis of lung cancer admitted to Cancer Hospital Affiliated to Xinjiang Medical University from January 2014 to January 2019 were analyzed retrospectively.According to different treatment methods,the patients were divided into observation group(n=99)and control group(n=90).The patients in observation group were treated with bronchial artery embolization,while the patients in control group were treated with conservative treatment.The coagulation fingers of the two groups were compared before and after treatment Standard,hemoptysis volume and clinical effect.Results After treatment,prothrombin time and fibrinogen in the observation group were(15.79±2.33)s,(1.18±0.31)g/L,which were significantly better than those in the control group(13.51±1.44)s,(2.56±0.44)g/L,the difference was statistically significant(P<0.05).After treatment,hemoptysis volume in the observation group was(102.27±14.21)ml,(74.29±6.31)ml,(22.17±2.45)ml,respectively.Compared with the control group,the difference was statistically significant(P<0.05).The total effective rates of the observation group and the control group were 90.9%and 61.1%,respectively,the difference was statistically significant(χ2=14.624,P<0.05).Conclusion Compared with conservative treatment,bronchial artery embolization can effectively improve the coagulation index of patients with massive hemoptysis of lung cancer,reduce the amount of hemoptysis,and the effect is reliable,which is worthy of clinical reference.

关 键 词：肺癌 大咯血 保守治疗 支气管动脉栓塞 凝血指标 

分 类 号：R734.2[医药卫生—肿瘤]