肥胖与摄盐量的关系研究  

Correlation between obesity and salt intake

作　　者：郎红梅 游志清 程莹 李文雯 刘君静 林宁 郭蔚 Lang Hongmei;You Zhiqing;Cheng Ying;Li Wenwen;Liu Junjing;Lin Ning;Guo Wei(Department of Endocrinology,the General Hospital of Western Theater Command;Department of Nutrition,the General Hospital of Western Theater Command)

机构地区：[1]西部战区总医院内分泌科,成都610083 [2]西部战区总医院营养科,成都610083

出　　处：《重庆医科大学学报》2020年第3期411-414,共4页Journal of Chongqing Medical University

基　　金：第63批博士后科学基金面上资助项目(编号:2018M633763)。

摘　　要：目的:探讨肥胖与盐摄入量的关系。方法:2017年9月至2018年7月,招募年龄在18~55岁的非妊娠成都城市社区健康人群226名,其中男性92名,女性134名。收集健康人24 h尿和血清,通过问卷调查收集一般信息。人群摄盐量通过检测24 h尿钠排泄来估算。根据摄盐量将人群分为低盐摄入组(<12 g/d)和高盐摄入组(≥12 g/d)。根据体质指数和腹围定义超重和肥胖。受试者空腹状态下按由低到高的顺序分别品尝不同浓度的氯化钠溶液,并指出味觉能识别的最低氯化钠浓度,检测盐味觉阈值。结果:肥胖与高盐摄入密切相关,体质指数与摄盐量成正比(P<0.001,r=0.223)。超重和肥胖者盐味觉敏感性降低,摄盐量明显高于正常体质量者[(13.50±0.37)g vs.(15.34±0.47)g,P=0.002],尤其是腹型肥胖患者。高盐摄入肥胖人群比例明显高于低盐摄入人群(78.64%vs.31.25%,P=0.016)。结论:肥胖与高盐摄入关系密切,超重和肥胖人群摄盐量增加,盐味觉敏感性降低。高盐摄入导致超重和肥胖患病率增加。Objective:To explore the relationship between salt intake and obesity.Methods:Two hundred and twenty-six healthy people aged 18-55 years from communities in Chengdu were enrolled in this study from September 2017 to July 2018,including 92 males and 134 non-pregnant females.24-hour urine and serum samples were collected from healthy people,and general information was obtained through questionnaire survey.Salt intake in the population was estimated by measuring 24-hour urine sodium excretion.According to the quantity of salt intake,the population was divided into low-salt intake group(<12 g/d)and high-salt intake group(≥12 g/d).Overweight and obesity were defined by body mass index(BMI)and abdominal circumference.The subjects tasted different concentrations of sodium chloride solution in a low-to-high order in the fasting state,and pointed out the minimum sodium chloride concentration,thus determining the salt taste threshold.Results:Obesity was closely related to high-salt intake,while BMI was in a positive correlation with salt intake(P<0.001,r=0.223).Cases with overweight and obesity had a lower salt taste sensitivity,and their salt intake was significantly higher than that of people with normal body weight[(13.50±0.37)g vs.(15.34±0.47)g,P=0.002],especially in abdominal obesity patients.The proportion of obese people was significantly higher in the population with high salt intake than in the population with low salt intake(78.64%vs.31.25%,P=0.016).Conclusion:Obesity is closely related to high salt intake.Overweight and obese patients have increased salt intake and reduced salt taste sensitivity.High salt intake leads to an increase in the prevalence of overweight and obesity.

关 键 词：肥胖 盐摄入量 盐味觉敏感性 

分 类 号：R723.14[医药卫生—儿科]