血浆置换技术在病毒感染类疾病治疗中的应用  

Application of plasma exchange in the treatment of viral infectious diseases

作　　者：欧亚青 陈璐 边原 舒永全 龙恩武 何林 闫峻峰 童荣生 OU Ya-qing;CHEN Lu;BIAN Yuan;SHU Yong-quan;LONG En-wu;HE Lin;YAN Jun-feng;TONG Rong-sheng(Individualized Drug Therapy Key Laboratory of Sichuan,Department of Pharmacy,Sichuan Academy of Medical Sciences,Sichuan Provincial People’s Hospital,Affiliated Hospital of University of Electronic Science and Technology of China,Chengdu 610072;School of Medicine,University of Electronic Science and Technology of China,Chengdu 610054)

机构地区：[1]四川省医学科学院四川省人民医院电子科技大学附属医院药学部个体化药物治疗四川省重点实验室,成都610072 [2]电子科技大学医学院,成都610054

出　　处：《中南药学》2020年第4期598-601,共4页Central South Pharmacy

基　　金：国家临床重点专科建设项目(No.30305030698);四川省省级公益性科研院所基本科研业务专项课题(No.2018YSKY0017);四川省人民医院院级科研基金临床研究及转化项目(No.2018LY09)。

摘　　要：血浆置换是一种体外血液净化技术,它将血浆连同溶于其中的自身抗体、免疫复合物、毒素等大分子物质清除,以减轻此类物质对机体的伤害。目前血浆置换技术广泛用于多种疾病的治疗。本文探讨了血浆置换技术在病毒感染类疾病(包括病毒性肝炎、甲型流感、传染性非典型肺炎、中东呼吸综合征)治疗中的应用,以期为新型冠状病毒肺炎等病毒感染类疾病的治疗提供参考。Plasma exchange is an in vitro blood purification technology,which removes the plasma together with macromolecular substances such as autoantibodies,immune complexes and toxins to reduce the harm of these substances to the body.At present,plasma exchange technology is widely used for diseases.This paper discusses the application of plasma exchange for viral diseases,such as including viral hepatitis,influenza A,severe acute respiratory syndrome,middle east respiratory syndrome,and aims to provide a reference for treatment of corona virus disease 2019.

关 键 词：血浆置换 病毒感染性疾病 病毒性肝炎 甲型流感 非典型肺炎 中东呼吸综合征 新型冠状病毒肺炎 

分 类 号：R575.3[医药卫生—消化系统]