重庆市涪陵地区人乳头瘤病毒流行病学特征  

Epidemiological characteristics of human papillomavirus in Fuling area of Chongqing

作　　者：刘琪[1] 杜超 邓文平[1] 汪婷[1] Liu Qi;Du Chao;Deng Wenping;Wang Ting(Medical Laboratory of Fuling Central Hospitol,Chongqing 408099,China)

机构地区：[1]重庆市涪陵中心医院医学检验科,408099

出　　处：《国际流行病学传染病学杂志》2020年第2期142-145,共4页International Journal of Epidemiology and Infectious Disease

摘　　要：目的了解重庆市涪陵区HPV流行病学特征。方法收集690名体检妇女的宫颈脱落细胞样本,采用基因扩增技术和导流杂交技术对其进行HPV DNA基因分型检测,并分析其感染率、亚型分布及与年龄相关性。结果690份样本中阳性126份,总阳性率为18.26%,其中高危型感染率为17.39%(120/690),占阳性样本数的95.24%,并以52、58、16、51、39和53型为主(共109份);单一感染为主(103份)。41~50岁的受检者感染率最高,达21.58%(71/329),且高危型占95.77%(68/71)。结论涪陵地区高危亚型HPV感染占比较高,有必要加强定期筛查和治疗,以减少HPV的传播,预防宫颈癌的发生。Objective To investigate the epidemiological characteristics of HPV in Fuling area of Chongqing.Methods There were 690 cervical cytological specimens collected from women during a routine examination in Fuling Center Hospital.HPV DNA genotypes were detected by gene magnification and flow-through hybridization.The prevalence of different subtypes,multiple coinfection and the relation with ages were analyzed.Results The total positive rate among 690 samples was 18.26%,and the positive rate of high-risk subtypes was 17.39%(120/690),accounting for 95.24%of all the positive cases,with the majority of HPV 52,58,16,51,39 and 53(109 cases);103 cases were single infection.Patients at 41-50 years old had the highest infection rate of 21.58%(71/329),and the high-risk type accounted for 95.77%(68/71).Conclusions The high-risk subtype HPV infection is high in Fuling area.It is necessary to strengthen regular screening and treatment,to reduce the spread of HPV and prevent the occurrence of cervical cancer.

关 键 词：乳头状瘤病毒感染 基因分型 宫颈癌 感染 

分 类 号：R737[医药卫生—肿瘤]