性别对小型猪基础麻醉效果的影响  

Gender-specific Differences on Basic Anesthetic Effect in Miniature Pigs

作　　者：刘天文[1] 李剑明[1] 王帆[1] 李军[1] 高作潮 赵梦 张杰民[1] LIU Tianwen;LI Jianming;WANG Fan;LI Jun;GAO Zuochao;ZHAO Meng;ZHANG Jiemin(TEDA International Cardiovascular Hospital,Tianjin 300457,China;Tianjin Solmax Technology Co.,Tianjin 300457,China;Tianjin AmCellGene Engineering Co.,Tianjin 300457,China)

机构地区：[1]泰达国际心血管病医院,天津300457 [2]天津索玛科技有限公司,天津300457 [3]天津昂赛细胞基因工程有限公司,天津300457

出　　处：《实验动物科学》2020年第1期66-68,73,共4页Laboratory Animal Science

基　　金：天津市科学技术委员会自然基金项目(No.17JCYBJC28200)。

摘　　要：目的探究性别对小型猪基础麻醉效果的影响。方法30只巴马香猪和24只农大Ⅱ系小型猪,雌雄各半。首剂量200 mg陆眠宁复合10 mg咪达唑仑,于耳后颈部肌注,完成基础麻醉。观察记录动物达到保定效果所用的时间以及追加药物的剂量。结果巴马香猪组,雌性较雄性平均追加30%~50%的首剂量;农大Ⅱ系组,雌性较雄性平均追加50%~100%的首剂量。结论研究表明性别影响小型猪的基础麻醉用药量和麻醉起效时间。加大对雌性个体的麻药剂量,可以缩短麻醉躁动期和手术准备时间。The purpose of this paper is to explore the effect of sex on basic anesthesia in miniature pigs.This experiment covered 30 Bama pigs and 24 NongdaⅡmini-pigs,half male and half female.All were injected intramuscularly in the neck with a dose of 200 mg Lumianning and 10 mg midazolam.Completed the basic anesthesia,observed and record the time taken for the animal to achieve the effect and the dosage of the additional drug.Finally in the Bama pigs group,the female needed an average initial dose of 30%~50%compared with the male.And NongdaⅡmini-pigs needed 50%~100%.So the conclusion is gender-specific differences affects the amount of basic anesthetic used and the effective time in miniature pigs.Increasing the dose of anesthetic to female individuals can shorten the period of anaesthesia and the time of operation.

关 键 词：性别 小型猪 基础麻醉 

分 类 号：R-332[医药卫生]