超声检查和PET/CT检查诊断甲状腺乳头状癌中央区淋巴结转移的对比研究  

Diagnostic values of ultrasound and PET/CT in center lymph node metastasis on papillary thyroid carcinoma

作　　者：汝琦 王清 潘林华[3] 丁媛 RU Qi;WANG Qing;PAN Linhua;DING Yuan(Department of Ultrasound, Qilu Hospital of Shandong University (Qingdao), Qingdao 266035, P.R.China;Molecular Imaging Department, Qingdao Center Hospital, Qingdao 266042, P.R.China;CT/MRI Room of Gaomi People’s Hospital, Gaomi 261500, P.R.China;Department of Special Examination, Qingdao Women and Children Hospital, Qingdao 266035, P.R.China)

机构地区：[1]山东大学齐鲁医院(青岛)超声科,山东青岛266035 [2]山东省青岛市中心医院分子影像科,山东青岛266042 [3]山东省高密市人民医院CT/MRI室,山东潍坊261500 [4]山东省青岛市妇女儿童医院特检科,山东青岛266035

出　　处：《医学影像学杂志》2020年第4期552-555,共4页Journal of Medical Imaging

摘　　要：目的比较超声检查和18F-FDG PET/CT检查对甲状腺乳头状癌中央区淋巴结转移的诊断价值。方法回顾性分析93例经病理证实的甲状腺乳头状癌患者中央区淋巴结转移情况,与术前超声检查和PET/CT检查对比,评价其诊断甲状腺乳头状癌中央区淋巴结转移的价值。结果超声检查诊断中央区淋巴结转移的敏感度、特异度、准确度、阳性预测值、阴性预测值分别是78.8%、61.0%、71.0%、71.9%、69.4%(χ^2=4.742,P=0.029);PET/CT检查诊断中央区淋巴结转移的敏感度、特异度、准确性、阳性预测值、阴性预测值分别是53.8%、78.0%、64.5%、75.7%、57.1%(χ^2=3.882,P=0.049)。超声检查和PET/CT检查诊断中央区淋巴结转移的ROC曲线下面积(AUC)分别为0.699、0.659。结论超声检查诊断甲状腺乳头状癌中央区淋巴结转移具有较高敏感度和准确性,且因其简便、分辨率高、无辐射等优势,较18F-FDG PET/CT检查更具有显著意义。Objective To evaluate the diagnostic efficacy of ultrasound and 18F-FDG PET/CT in center lymph node metastasis on papillary thyroid carcinoma.Methods A total of 93 patients with papillary thyroid carcinoma who had undergone total or subtotal thyroidectomy and center lymph node dissection were analyzed retrospectively.The receiver operating characteristic curve(ROC)was used to investigate the diagnostic values of ultrasound and 18F-FDG PET/CT.Results The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of ultrasound were 78.8%,61.0%,71.0%,71.9%,69.4%(χ^2=4.742,P=0.029),respectively.Those of 18F-FDG PET/CT were 53.8%,78.0%,64.5%,75.7%,57.1%(χ^2=3.882,P=0.049),respectively.The areas under the ROC curve(AUC)were 0.699,0.659,respectively.Conclusion Compared with 18F-FDG PET/CT,ultrasound has higher efficacy in diagnose of center lymph node metastasis on papillary thyroid carcinoma.

关 键 词：甲状腺肿瘤 超声检查 正电子发射断层成像/计算机断层成像 淋巴结转移 

分 类 号：R736.1[医药卫生—肿瘤] R445[医药卫生—临床医学]