Electroacupuncture for post-stroke anxiety disorder on the base of the heart-brain theory:A randomized controlled trial  

从心脑论治电针中风后焦虑障碍:随机对照试验

作　　者：Ran LIU San-san CHEN Jun WANG 刘然;陈三三;王军(河南中医药大学第一附属医院儿科,郑州450000;北京市丰台区马家堡卫生服务中心针灸科,北京100071;北京中医药大学东直门医院针灸科,北京100700)

机构地区：[1]Department of Pediatrics,the First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China [2]Department of Acupuncture and Moxibustion,Majiapu Health Service Center,Fengtai District,Beijing 100071,China [3]Department of Acupuncture and Moxibustion,Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing 100700,China

出　　处：《World Journal of Acupuncture-Moxibustion》2020年第1期23-28,共6页世界针灸杂志（英文版）

基　　金：Supported by State Administration of Traditional Chinese Medicine,National Traditional Chinese Medicine Clinical Research Base Business Construction Special Research Project:JDZX 2015313.

摘　　要：Objective:To evaluate the differences in the clinical effect and the safety in the treatment of post-stroke anxiety disorder(PSAD)between electroacupuncture(EA)and paroxetine on the base of the heart-brain theory.Methods:A total of 70 patients of PSAD were randomized into an EA group and a medication group,35 cases in each one.In the EA group,four acupoints were selected and divided into two pairs.In the Pair A,there were Baihui(百会GV20)and Fengfu(风府GV16).In the Pair B,there were Xinshu(心俞BL15)and Shenmen(神门HT7).After acupuncture,the electroacupuncture apparatus was applied.The duration of needle retention was 20 min.EA was given three times a week,totally for 4 weeks.In the medication group,paroxetine tablets were administered orally,10 mg daily in the first 4 days and 20 mg afterwards,totally for 4 weeks.Before and after treatment,as well as in the follow-up period,Hamilton anxiety scale(HAMA),Barthel index(BI)for daily life ability,and clinical global impression(CGI)were observed and the clinical therapeutic effect was evaluated separately.Results:A total of 3 cases were dropped-out in the medication group.Finally,35 cases in the EA group and 32 cases in the medication group were included in the analysis.Compared with the scores before treatment,the scores of HAMA and CGI-SI(severity of illness)were lower and the scores of BI were higher after treatment and during the follow-up in either the EA group or the medication group(all P<0.05).Compared with the scores after treatment,the differences were not significant in HAMA and CGISI scores during the follow-up in either the EA group or the medication group(all P>0.05).Compared with the medication group,BI score in the EA group was higher in the follow-up,indicating the statistical significance(P<0.05).After treatment,CGI-SI score was different statistically between the EA group and the medication group(P<0.05).There were 5 cases with adverse reactions in the EA group and 9 cases in the medication group.Conclusions:The therapeutic effect of electroa

关 键 词：ELECTROACUPUNCTURE Brain-heart THEORY PAROXETINE POST-STROKE ANXIETY disorder 

分 类 号：R246.6[医药卫生—针灸推拿学]