Micromotor-derived composites for biomedicine delivery and other related purposes  

作　　者：Xiang Xu Zhiyi Huo Jiaming Guo Hao Liu Xiaole Qi Zhenghong Wu 

机构地区：[1]Key Laboratory of Modern Chinese Medicines,China Pharmaceutical University,Nanjing 210009,People's Republic of China

出　　处：《Bio-Design and Manufacturing》2020年第2期133-147,共15页生物设计与制造（英文）

基　　金：This work was supported by the National Natural Science Foundation of China(No.51472115);the Jiangsu Provincial Graduate Research Innovation and Practice Project(KYCX17_0672,KYCX19_0645);the Research Program of Natural Science in Huaian(HAB201717);and the Jiangsu Overseas Research&Training Program for University Young Faculty and Presidents.

摘　　要：Biocompatible designed micromotor has attracted more and more concerns in the field of biomedicine due to their self-propulsion and delivery abilities.Such micromotors,mostly consisting of alkali earth metals,hydrogels,or other motile biomaterials,can effectively transform chemical energy into mechanical or kinetic energy to achieve the expected delivery of cargos to the sites of action.Except for conveying power,the modifiable surface and inner cavity of micromotors guarantee that their potential as versatile delivery systems for therapeutic agents.Here,this review generalizes the propelling mechanisms,composites,and shapes of micromotors.Besides,the application of micromotor-derived composites for biomedicine delivery and other versatile purposes are also discussed.

关 键 词：MICROMOTOR PROPULSION TARGETED delivery RETENTION PENETRATION 

分 类 号：R318.08[医药卫生—生物医学工程]