胰头区恶性肿瘤术后预后因素的研究进展  

Prognostic factors of malignant tumors in the head of pancreas after operation

作　　者：冉东辉 娄子彦 耿诚[1] 徐新建[1] RAN Donghui;LOU Ziyan;GENG Cheng;XU Xinjian(Department of Pancreatic Surgery,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,P.R.China)

机构地区：[1]新疆医科大学第一附属医院胰腺外科,乌鲁木齐830054

出　　处：《中国普外基础与临床杂志》2020年第5期646-652,共7页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探讨包含壶腹部、胆管下段、胰头部、钩突部和胰颈部5个部位在内的胰头区恶性肿瘤术后的预后影响因素。方法对近年国内外有关该区域恶性肿瘤研究的文献结果进行归纳综述。结果壶腹部、胆管下段、胰头部、钩突部和胰颈部恶性肿瘤的预后与其病变部位、肿瘤直径、神经侵犯、血管侵犯、淋巴转移、病理学及组织学分型和切缘状态存在相关性。肿瘤位置及病理学分型的不同使其神经血管侵犯率、淋巴转移率和R0切除率存在差异。结论通过对肿瘤病变部位、肿瘤直径、神经侵犯、血管侵犯、淋巴转移、病理及组织学分型和切缘状态的总结分析,可提高对该区域肿瘤的临床预判准确性,有利于术前选择恰当的手术方式,术后制定更为合理的辅助治疗方案,提高人们对该区域肿瘤治疗的针对性,改善预后,以便更好地服务于临床工作。Objective To explore the prognostic factors of malignant tumors in ampulla,lower bile duct,head of pancreas,uncinate process,and neck of pancreas after operation. Method The recent literatures on malignant tumors in this region at home and abroad were summarized. Results The prognosis of five groups of malignant tumors in ampulla,lower bile duct,head of pancreas,uncinate process,and neck of pancreas was correlated with their origin,growth site,tumor diameter,nerve invasion,vascular invasion,lymphatic metastasis,pathological and histological classification,and cutting edge status. The different location and pathological classification of tumors made the different neurovascular invasion rate,lymphatic metastasis rate,and R0 resection rate. Conclusions By summarizing and analyzing the origin,growth site,diameter,nerve invasion,vascular invasion,lymphatic metastasis,pathological and histological classification,and cutting edge status of tumors,we can improve the clinical prediction of tumors in this region,select appropriate surgical methods before operation,and formulate more reasonable adjuvant treatment plan after operation,in order to improve the pertinence of the treatment of tumors in this region,improve the prediction,and finally better serve the clinical work.

关 键 词：胰头癌 壶腹癌 胆管下段癌 胰十二指肠切除术 预后 综述 

分 类 号：R735.9[医药卫生—肿瘤]