OCTA在糖尿病视网膜病变的临床应用研究进展  

Research advances on clinical application of OCTA in diabetic retinopathy

作　　者：李沐叶 张学东[1] LI Muye;ZHANG Xuedong(Department of Ophthalmology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属第一医院眼科,重庆市400010

出　　处：《眼科新进展》2020年第5期482-486,共5页Recent Advances in Ophthalmology

基　　金：国家自然科学基金项目(编号81870673)。

摘　　要：光学相干断层扫描血管成像(optical coherence tomography angiography,OCTA)是光学相干断层扫描(optical coherence tomography,OCT)继时域OCT和频域OCT之后的另一个里程碑。OCTA扫描更快、更密集,可以提取变化的OCT信号,在不注射造影剂的前提下安全、快速地获得高分辨率的三维视网膜及脉络膜血管信息,对于眼底疾病的观察和随访具有积极重要的意义。糖尿病视网膜病变(diabetic retinopathy,DR)是工作年龄人群首位致盲疾病。本文将综述OCTA的基本原理,以及其在DR的临床应用,通过了解其不同阶段的OCTA表现,以期改善DR的诊断和治疗水平。Optical coherence tomography angiography(OCTA)is the next milestone of optic coherence tomography(OCT)after stratus OCT and spectral domain OCT.OCTA scans are faster and denser,provide changing OCT signals and high-definition information of a three-dimensional reconstruction of retinal and choroidal vasculatures quickly as well as densely.It is very important to observe and follow up the fundus diseases.Diabetic retinopathy(DR)is the first blinding disease for people in working age.This article reviews the basic principle of OCTA and its clinical applications in DR,in order to provide reference value for the diagnosis and treatment of DR by understanding different OCTA features of DR lesions at different courses.

关 键 词：光学相干断层扫描血管成像 糖尿病视网膜病变 黄斑中心凹无血管区 视网膜微血管瘤 视网膜血管密度 视网膜新生血管 

分 类 号：R774.1[医药卫生—眼科]