铁路系统职工胆囊结石患病情况及其危险因素分析  

Prevalence of Cholecystolithiasis and Its Risk Factors in Railway System Workers

作　　者：向红铭 易尚辉[1] 吕媛[1] 查文婷[1] 王凯旋 XIANG Hong-ming;YI Shang-hui;LYU Yuan;ZHA Wen-ting;WANG Kai-xuan(Hunan Key Laboratory of Molecular Epidemiology,Medical College of Hunan Normal University,Changsha 410013,Hunan,China)

机构地区：[1]湖南师范大学医学院分子流行病学湖南省重点实验室,湖南长沙410013

出　　处：《医学信息》2020年第5期126-129,共4页Journal of Medical Information

基　　金：湖南省教育厅(编号:湘教通[2017]452号、湘教通[2017]451号)。

摘　　要：目的了解铁路系统职工胆囊结石患病情况及其危险因素,为开展特定职业人群胆囊结石防治提供理论依据。方法选取2016年5月~2018年6月铁路系统中8个铁路段接受体检的13724名职工的体检资料,均进行常规体格检查,临床指标检测,B超影像学等检查,根据胆囊结石诊断标准分为正常组和异常组,比较两组体检资料,并采用多因素Logistic回归分析胆囊结石的影响因素。结果13724名铁路系统在职职工,其中异常组925例,正常组12799人。两组性别、尿胆红素、血肌酐、尿素氮、隐血、谷丙转氨酶、谷草转氨酶、总胆红素、总胆固醇、LDL-C、促甲状腺、甲胎蛋白、癌胚抗原、EB病毒抗体比较,差异无统计学意义(P>0.05);两组年龄、BMI、高血压、血糖、脂肪肝、尿葡萄糖、尿蛋白质、甘油三酯、HDL-C比较,差异有统计学意义(P<0.05)。多因素非条件Logistic回归分析显示,高龄、超重肥胖、高血压、高血糖、脂肪肝、低HDL-C是铁路系统职工胆囊结石患病的危险因素。结论铁路系统职工胆囊结石患病率较高,高龄、超重肥胖、血糖偏高、高血压、脂肪肝、低HDL-C水平为铁路系统职工胆囊结石患病的危险因素。因此,加强对职工血压、血糖检测,调节膳食结构,减少饱和脂肪摄入,控制体重,积极预防脂肪肝和脂类代谢疾病等可有效预防胆囊结石患病的风险。Objective To understand the prevalence of cholecystolithiasis and its risk factors in railway system workers,and to provide theoretical basis for the prevention and treatment of cholecystolithiasis in specific occupational groups.Methods Selected the physical examination data of 13,724 employees who underwent physical examination in 8 railway sections in the railway system from May 2016 to June 2018,All undergo a routine physical examination,clinical index testing,B-ultrasound imaging and other examinations,according to the diagnostic criteria of cholecystolithiasis,they were divided into normal group and abnormal group.The physical examination data of the two groups were compared,and the influencing factors of cholecystolithiasis were analyzed by multivariate Logistic regression.Results A total of 13,724 people are employed in the railway system,including 925 cases in the abnormal group and 12,799 in the normal group.Gender,urine bilirubin,blood creatinine,urea nitrogen,occult blood,alanine aminotransferase,aspartate aminotransferase,total bilirubin,total cholesterol,LDL-C,thyroid-stimulating protein,alpha-fetoprotein,carcinoembryonic antigen,EB virus antibody,there was no significant difference in comparison(P>0.05);there was significant difference in age,BMI,hypertension,blood glucose,fatty liver,urinary glucose,urinary protein,triglycerides,HDL-C between the two groups(P<0.05).Multivariate non-conditional Logistic regression analysis showed that old age,overweight and obesity,high blood pressure,high blood sugar,fatty liver,and low HDL-C were risk factors for the occurrence of cholecystolithiasis in employees of the railway system.Conclusion The prevalence of cholecystolithiasis in railway system workers is high.Old age,overweight and obesity,high blood sugar,high blood pressure,fatty liver,and low HDL-C levels are risk factors for the disease of railway system workers.Therefore,strengthening the detection of blood pressure and blood sugar of employees,adjusting dietary structure,reducing saturated fat intake

关 键 词：铁路系统 胆囊结石 危险因素 

分 类 号：R575.6[医药卫生—消化系统]