抗菌光动力疗法在口腔疾病中应用的研究进展  

Research Progress in Antimicrobial Photodynamic Therapy for Oral Diseases

作　　者：欧阳兰兰 汪建中[1] OUYANG Lan-lan;WANG Jian-zhong(Department of Stomatology,Jiangxi Provincial People’s Hospital,Nanchang 330006,China)

机构地区：[1]江西省人民医院口腔科,南昌330006

出　　处：《实用临床医学（江西）》2020年第2期102-104,共3页Practical Clinical Medicine

摘　　要：抗菌光动力疗法(antimicrobial photodynamic therapy,aPDT)在口腔疾病的体内体外实验中呈现出积极的效果。本文主要对光动力疗法(PDT)在牙周病、种植体周病、牙体牙髓病、口腔黏膜感染等口腔疾病抗菌治疗中的有效性进行阐述。指出PDT在治疗口腔感染疾病具有潜在的应用价值,但其技术标准有待统一;光敏剂和光源未被分类,如何组合才能获得临床理想的杀菌效果,激活光源和光敏剂类型在PDT中的具体作用等等问题还有待探究。Antimicrobial photodynamic therapy(aPDT)has shown positive results in in vitro and in vivo experiments on oral diseases.This article mainly describes the effectiveness of photodynamic therapy(PDT)in antibacterial treatment of oral diseases,such as periodontal disease,peri-implantitis,endodontic disease and oral mucosal infection.The PDT has potential application value in the treatment of oral infection,but its technical standards need to be unified.Because photosensitizers and light sources are not classified,how to achieve the ideal bactericidal effect and how to activate the specific role of light sources and photosensitizers in PDT remain to be explored.

关 键 词：抗菌光动力疗法 光动力疗法 口腔疾病 有效性 

分 类 号：R781[医药卫生—口腔医学]