不同强度的经颅直流电刺激对脑梗死后吞咽障碍患者的疗效比较  

Intensities of Transcranial Direct Current Stimulation for Dysphagia after Cerebral Infarction

作　　者：杜宇鹏[1] 李晓东[1] 刘文兵[1] 刘雪云[1] DU Yu-peng;LI Xiao-dong;LIU Wen-bing;LIU Xue-yun(The Third Affiliated Hospital of Zhejiang Chinese Medicine University,Hangzhou,Zhejiang 310000,China)

机构地区：[1]浙江中医药大学附属第三医院,浙江杭州市310000

出　　处：《中国康复理论与实践》2020年第5期583-587,共5页Chinese Journal of Rehabilitation Theory and Practice

基　　金：浙江省自然科学基金项目(No.LQ16H170001,No.LQ19H170002);浙江省医药卫生科技计划项目(No.2015KYB279);浙江中医药大学附属第三医院医药卫生科技计划项目(No.ZS15CA15)。

摘　　要：目的探讨经颅直流电刺激(tDCS)对脑梗死后吞咽障碍的有效强度及其神经机制。方法2016年1月至2018年12月,脑梗死后吞咽障碍住院患者60例随机分为低强度组(n=20)、中强度组(n=20)和高强度组(n=20),分别给予1.0 mA、1.5 mA和2.0 mA tDCS,共30 d。治疗前后观察吞咽造影和脑电α波变化。结果与治疗前相比,高强度组口腔期评分升高(t=-2.196,P<0.05),α波优势频率显著升高(t=-6.488,P<0.001)。结论高强度tDCS可提高脑梗死后吞咽障碍患者脑兴奋性,改善吞咽功能。Objective To study the effects of transcranial direct current stimulation(tDCS)in different intensities on dysphagia after cerebral infarction and its neurological mechanism.Methods From January,2016 to December,2018,60 inpatients with dysphagia after cerebral infarction were randomly equally divided into low-,medium-and high-intensity groups,in which the intensities of tDCS were 1.0 mA,1.5 mA and 2.0 mA,respectively,for 30 days.They were observed with video fluoroscopic swallowing study andαwaves of electroencephalography before and after treatment.Results The score of oral stage increased in the high-intensity group after treatment(t=-2.196,P<0.05),while the dominant frequency ofαwave increased(t=-6.488,P<0.001).Conclusion High-intensity tDCS may improve the excitability of the brain for patients with dysphagia after cerebral infarction,to improve the swallowing.

关 键 词：脑梗死 吞咽障碍 经颅直流电刺激 脑电图 

分 类 号：R743.32[医药卫生—神经病学与精神病学]