高频超声诊断乳腺佩吉特病的价值  

Diagnostic value of high-frequency ultrasonography for Paget disease of breast

作　　者：陈蕾[1] 刘菊梅 梁振威 陈路增[1] CHEN Lei;LIU Jumei;LIANG Zhenwei;CHEN Luzeng(Department of Ultrasound,Peking University First Hospital,Beijing 100034,China;Department of Pathology,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院超声医学科,北京100034 [2]北京大学第一医院病理科,北京100034

出　　处：《中国介入影像与治疗学》2020年第5期299-302,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：北京大学第一医院交叉临床研究专项科研基金(2018CR30);北京大学第一医院科研种子基金(2019SF46)。

摘　　要：目的观察高频超声对乳腺佩吉特病(PDB)的诊断价值。方法回顾性分析经病理证实的30例PDB患者的乳腺高频超声资料,其中13例合并浸润性导管癌(IDC),比较PDB合并与未合并IDC患者乳腺超声表现的差异。结果PDB超声表现包括乳头内低回声、乳晕皮肤增厚、乳腺内结节、钙化、导管扩张及腋窝淋巴结肿大。PDB合并IDC患者超声显示结节率(P=0.001)及腋窝淋巴结肿大率(P=0.002)均高于未合并IDC者,超声显示二者乳腺影像报告和数据系统(BI-RADS)分类、乳头内低回声、乳晕皮肤增厚、钙化及乳腺导管扩张比例差异均无统计学意义(P均>0.05)。结论PDB超声表现具有一定特征性,高频超声有助于诊断及评估病情。Objective To investigate the diagnostic value of high-frequency ultrasound for Paget disease of breast(PDB).Methods High-frequency ultrasound data of 30 patients with pathology approved PDB were retrospectively analyzed,including 13 cases complicated with invasive ductal carcinoma(IDC).Ultrasonic appearances of PDB with or without IDC were compared.Results Ultrasonic features of PDB included hypo-echogenicity in nipple,thicken areola skin,mammary nodules,calcification,dilated duct and enlarged axillary lymph nodes.Compared with PDB without IDC,PDB complicated with IDC showed more mammary nodules(P=0.001)and enlarged axillary lymph nodes(P=0.002).No significant difference of breast imaging reporting and data system(BI-RADS)classification,hypo-echogenicity in nipple,thicken areola skin,calcification nor dilated duct rate was found between groups(all P>0.05).Conclusion PDB have certain ultrasonic characteristics.High-frequency ultrasound is helpful to diagnosis and assessment of PDB.

关 键 词：佩吉特病 乳腺 癌 导管 超声检查 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]