肠道菌群与肝癌的相关研究进展  

The Research Progress in Correlation of Intestinal Flora with Liver Cancer

作　　者：许文倩 方路 段秋香 陈程[1] 彭彬峰 姜孝新[1] XU Wenqian;FANG Lu;DUAN Qiuxiang;CHEN Cheng;PENG Binfeng;JIANG Xiaoxin(The First Affiliated Hospital,University of South China,Hengyang,Hunan,421001,China)

机构地区：[1]南华大学附属第一医院,湖南衡阳421001

出　　处：《肿瘤药学》2020年第2期154-158,共5页Anti-Tumor Pharmacy

基　　金：湖南省重点研发计划项目(2018SK2095)。

摘　　要：肝癌是全世界最常见的恶性肿瘤之一,发病率和死亡率分别位居第六和第三。近年来,微生物组这一概念逐渐走入人们的视野,尤其是肠道微生物在肿瘤治疗中的作用获得了越来越多的关注。有研究表明,肝癌的发生发展与肠道菌群有着十分紧密的联系。本文就肝癌与肠道菌群之间的研究进展作一综述。Liver cancer is one of the most common malignant tumors in the world.It ranks the sixth in morbidity and the third in mortality.In recent years,the concept of microbiome has gradually come into people's field of vision,especially the role of intestinal microorganisms in tumor therapy.Studies have shown that there is a close relationship between intestinal flora and the occurrence and development of liver cancer.This paper reviews the research progress in correlation of liver cancer with intestinal flora.

关 键 词：肠道菌群 肝癌 肠上皮功能 胆汁酸 白细胞介素 

分 类 号：R735.7[医药卫生—肿瘤]