颅脑外伤性癫痫发病的危险因素分析  

Analysis on Risk Factors for Post-Traumatic Epilepsy Attack

作　　者：陈满凝 李尧 陈义章 CHEN Manning;LI Yao;CHEN Yizhang(Chaozhou People's Hospital,Chaozhou 521000,China)

机构地区：[1]潮州市人民医院,广东潮州521000

出　　处：《临床医学工程》2020年第5期681-682,共2页Clinical Medicine & Engineering

摘　　要：目的探讨颅脑外伤性癫痫(PTE)发病的危险因素。方法选取我院神经外科2016年1月至2019年10月收治的120例颅脑外伤患者,既往均有癫痫史,分为PTE组和非PTE组各60例。分析两组的临床因素,采用Logistic回归分析PTE发病的危险因素。结果单因素分析结果显示,PTE发病与年龄、严重程度(GCS)、受伤部位、凹陷性颅骨骨折相关(P <0.05),与性别、蛛网膜下腔出血无相关性(P>0.05)。多因素Logistic回归分析结果显示,年龄(OR=0.652, 95%CI:1.246~2.419),严重程度(GCS)(OR=2.041, 95%CI:1.394~4.842)、受伤部位(OR=1.642, 95%CI:2.105~4.378)、凹陷性颅骨骨折(OR=6.548, 95%CI:1.541~3.547)为PTE发病的影响因素。结论年龄、严重程度(GCS)、受伤部位、凹陷性颅骨骨折为PTE发病的影响因素,临床中应针对PTE发病因素进行预防和及时治疗,以提高临床疗效和预后。Objective To explore the risk factors for post-traumatic epilepsy(PTE) attack. Methods 120 cases of patients with craniocerebral trauma and history of epilepsy admitted to our neurosurgery department from January 2016 to October 2019 were selected and divided into PTE group and non-PTE group, with 60 cases in each group. The clinical factors of the two groups were analyzed. Logistic regression was used to analyze the risk factors of PTE attack. Results Univariate analysis results showed that PTE attack was correlated with age, severity(GCS), injured part and depressed skull fracture(P <0.05), and was not correlated with gender and subarachnoid hemorrhage(P>0.05). Multivariate Logistic regression analysis results showed the age(OR = 0.652, 95%CI: 1.246 ~ 2.419), severity(GCS)(OR = 2.041,95%CI: 1.394 ~ 4.842), injury part(OR = 1.642, 95%CI: 2.105 ~ 4.378) and depressed skull fracture(OR = 6.548, 95%CI: 1.541 ~ 3.547)were the influencing factors of PTE attack. Conclusions Age, severity(GCS), injured part and depressed skull fracture are the influencing factors of PTE attack. PTE attack factors should be prevented clinically and treated in time so as to improve the clinical effect and prognosis.

关 键 词：颅脑外伤性癫痫 危险因素 蛛网膜下腔出血 凹陷性颅骨骨折 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R651.15[医药卫生—临床医学]