放疗计划自动分析系统的开发研究  

Development of an automatic analysis system for radiotherapy planning

作　　者：杨成文[1] 冯远明[1] 王平 郭露 王伟 Yang Chengwen;Feng Yuanming;Wang Ping;Guo Lu;Wang Wei(School of Precision Instruments&Opto-Electronics Engineering,Tianjin University,Tianjin 300072,China;National Clinical Research Center for Cancer,Cancer Hospital,Tianjin Medical University,Tianjin 300060,China)

机构地区：[1]天津大学精密仪器与光电子工程学院,300072 [2]天津医科大学肿瘤医院国家肿瘤临床医学研究中心,300060

出　　处：《中华放射肿瘤学杂志》2020年第5期358-362,共5页Chinese Journal of Radiation Oncology

基　　金：国家重点研发计划资助(2017YFC0113100)。

摘　　要：目的开发一款放疗计划自动分析系统,通过智能解析Pinnacle3治疗计划系统(TPS)的治疗计划底层数据,实现放疗计划剂量参数的自动化分析。方法将12例接受放射治疗的食管癌患者的治疗计划纳入研究。自动分析系统自动检索Pinnacle3 TPS数据库,获取12例治疗计划原始数据,并自动解析底层原始数据,重建轮廓、射野和剂量参数,并重新计算剂量分布和"剂量-体积"直方图。通过与在线TPS中原始计划输出体积和剂量数据进行对比,来评估新系统重新计算体积和剂量数据的准确性。结果自动分析系统成功解析治疗计划的底层数据,并重建治疗计划参数。新系统计算轮廓的体积与原计划的体积偏差≤0.1%;重新计算GTV、PGTV、CTV和PTV的Dmax、Dmean、D95和D50等参数,与原计划的剂量偏差≤1.0%;重新计算ROIs的Dmax和Dmean,与原计划的剂量偏差<5%。结论自动分析系统可直接分析Pinnacle3 TPS治疗计划的底层数据,重建治疗计划,计算轮廓体积和剂量参数,与原计划的剂量偏差满足临床要求。Objective An automatic analysis system for radiotherapy planning was developed to realize the automatic analysis of dose parameters of radiotherapy planning through the intelligent analysis of the underlying data of Pinnacle3 treatment planning system(TPS).Methods The radiotherapy plans of 12 patients with esophagus cancer were analyzed.The automatic analysis system automatically retrieved the Pinnacle3 TPS database,obtained the raw data of 12 cases of treatment plan,and automatically analyzed the underlying raw data,reconstructed contours,radiation fields,and dose parameters,and recalculated dose distribution and dose-volume histograms.The accuracy of the recalculation of the volume and dose data of the new system was evaluated by comparing with volume and dose data from the original plans of online TPS.Results The automatic analysis system successfully parsed the underlying data of the treatment plan and reconstructed the parameters of the treatment plan.The volume deviation between the contour calculated by the new system and the original plans was≤0.1%;Compared with the reference dose of the original plans,the deviations of dose parameters(Dmax,Dmean,D95,and D50 for GTV,PGTV,CTV,and PTV)recalculated by the new analysis system were≤1.0%;The deviations of Dmax and Dmean of recalculated ROIs from the original plans were<5%.Conclusions The automatic analysis system can directly analyze the underlying data of the Pinnacle3 TPS treatment plan,reconstruct the treatment plan,calculate the contour volume and dose parameters,and the dose deviations from the original plans meet clinical requirements.

关 键 词：治疗计划系统 自动分析系统 剂量参数 "剂量-体积"直方图 

分 类 号：R730[医药卫生—肿瘤]