酒依赖认知损害与同型半胱氨酸的研究进展  

Research progress on cognitive impairment and homocysteine in alcohol dependence

作　　者：徐琳[1] 王学义[1] Xu Lin;Wang Xueyi(Department of Psychiatry,the First Hospital of Hebei Medical University,Menial Health Institute of Hebei Medical University,Brain Aging and Cognitive Neuroscience Laboratory,Shijiazhuang 050031,China)

机构地区：[1]河北医科大学第一医院精神卫生中心河北医科大学精神卫生研究所河北省脑老化与认知神经科学重点实验室,石家庄050031

出　　处：《神经疾病与精神卫生》2019年第12期1084-1088,共5页Journal of Neuroscience and Mental Health

摘　　要：长期饮酒可导致认知损害,但具体机制尚不明确.血浆同型半胱氨酸水平升高与酒依赖所致认知损害密切相关,现从同型半胱氨酸的生物效应、与酒精相关认知损害的关系及治疗进展等几方面对同型半胱氨酸与酒依赖所致认知损害的研究加以综述.Chronic alcohol consumption can induce cognitive impairment,whereby the exact mechanism remains unknown.Elevated plasma homocysteine level are closely related to cognitive impairment in alcohol-dependent patients.This article reviews the research of homocysteine and cognitive impairment in alcohol dependent patients,from the aspects of biological effects of homocysteine,the relationship between homocysteine and alcohol-related cognitive impairment,and treatment progress.

关 键 词：酒依赖 认知损害 同型半胱氨酸 多态性 单核苷酸 综述 

分 类 号：R74[医药卫生—神经病学与精神病学]