毛发样本的前处理技术研究进展  

Advances in pretreatment techniques for hair samples

作　　者：李超 王继芬 王燕燕[2] LI Chao;WANG Ji-fen;WANG Yan-yan(School of Criminal Science and Technology,People’s Public Security University of China,Beijing 100038,China;Beijing Municipal Public Security Bureau Judicial Appraisal Center,Key Laboratory of Toxic Analysis of the Ministry of Public Security,Beijing 100192,China)

机构地区：[1]中国人民公安大学刑事科学技术学院,北京100038 [2]北京市公安局司法鉴定中心,法庭毒物分析公安部重点实验室,北京100192

出　　处：《药物分析杂志》2020年第3期401-412,共12页Chinese Journal of Pharmaceutical Analysis

基　　金：中国人民公安大学基科费项目(2019JKF223);广东省化学危害应急检测技术重点实验室开放基金(KF2018002)资助。

摘　　要：在法庭科学中,毛发分析发挥着越来越重要的作用。毛发分析提供了其他生物检材(如血液和尿液)所没有的独特优势,包括较长的检测时间窗口、易于收集和样本稳定。本文综述了近年来国内外毛发样本前处理技术的发展,简述了毛发分析过程中去污、提取和纯化步骤,同时就不同种类毒品,总结了所需的有机溶剂、提取方法和纯化方式。In forensic science,hair analysis plays an increasingly important role. Hair analysis provides unique advantages not found in other biopsies such as blood and urine,including longer detection windows,ease of collection,and sample stability. In this paper,the development of hair sample pretreatment techniques at home and abroad in recent years is reviewed. The decontamination,extraction and purification steps in the hair analysis process are briefly described. At the same time,the required organic solvents,extraction methods and purifications are summarized for different kinds of drugs.

关 键 词：毛发 法庭科学 前处理技术 酸消解 碱消解 球形研磨甲醇超声提取 仪器分析 

分 类 号：R917[医药卫生—药物分析学]