无创性标志物在诊断早期子宫内膜异位症中价值的研究进展  

Research advances in the value of noninvasive markers in the early diagnosis of early endometriosis

作　　者：徐彦 顾振鹏[1] 李芳芳[1] 刘志慧[1] 崔金秀[1] XU Yan;GU Zhen-peng;LI Fang-fang;LIU Zhi-hui;CUI Jin-xiu(Department of Obstetrics and Gynecology,Binzhou Medical University Hospital,Shandong Province,Binzhou256600,China)

机构地区：[1]滨州医学院附属医院妇产科,山东滨州256600

出　　处：《中国当代医药》2020年第15期36-39,43,共5页China Modern Medicine

摘　　要：子宫内膜异位症作为妇科常见病困扰着众多育龄期妇女,近年来因其高发病率、高复发率和年轻化趋势备受关注,更因其具有类似恶性肿瘤的侵袭、种植行为而被人们戏称为“良性癌”,对女性的生活质量造成了严重的影响。诊断子宫内膜异位症的“金标准”是腹腔镜检查,不仅价格高昂、需要全身麻醉,甚至可能会导致盆腹腔粘连等并发症。目前,CA125是临床上最常用于预测子宫内膜异位症的指标,但并非早期诊断的可靠工具。由于缺乏特异性的临床症状及无创性的早期检测手段,子宫内膜异位症常常被延迟诊断,甚至漏诊。因此寻求一种高特异性和高敏感性的无创性生物学指标来诊断早期子宫内膜异位症显得至关重要。本文主要阐述无创性生物学指标在子宫内膜异位症早期诊断中的价值。Endometriosis,as a common gynecological disease,has affected many women of childbearing age.In recent years,because of its high incidence,high recurrence rate,and younger tendencies,much more attention has been paid,and because of its invasion and implantation behavior similar to malignant tumors,it has been nicknamed the"benign carcinoma",which has caused serious impact on life quality of women.The"gold standard"for the diagnosis of endometriosis is laparoscopy,which is not only expensive,requires general anesthesia,and may even cause complications such as pelvic and abdominal adhesions.At present,CA125 is the most commonly used clinical indicator to predict endometriosis,but it is not a reliable tool for early diagnosis.Due to the lack of specific clinical symptoms and noninvasive early detection methods,the diagnosis of endometriosis is often delayed or even missed.Therefore,it is very important to seek a noninvasive biological index with high specificity and sensitivity to diagnose early endometriosis.This paper mainly expounds the value of noninvasive biological index in the early diagnosis of endometriosis.

关 键 词：子宫内膜异位症 早期诊断 无创性标志物 

分 类 号：R714[医药卫生—妇产科学]