肢体远隔缺血预适应对脑梗死患者预后的影响  

Influence of remote ischemic preconditioning on the prognosis of patients with cerebral infarction

作　　者：刘华[1] 黄斌英[1] 王艳婵[1] LIU Hua;HUANG Bin-ying;WANG Yan-chan(Department of Outpatient,the Twelfth People′s Hospital of Guangzhou City,Guangdong Province,Guangzhou 510620,China)

机构地区：[1]广州市第十二人民医院门诊部,广东广州510620

出　　处：《中国当代医药》2020年第13期40-43,共4页China Modern Medicine

摘　　要：目的探讨肢体远隔缺血预适应(RIPC)对脑梗死患者预后的影响。方法选取2015年1月~2016年1月我院收治的104例脑梗死患者作为研究对象,采用电脑随机法将其划分为观察组与对照组,每组各52例。观察组患者采用常规药物治疗联合RIPC护理干预,对照组患者采用常规护理+药物治疗。评价两组患者干预前后的美国国立卫生研究院卒中量表(NIHSS)评分,比较两组的脑缺血再发生率、生活质量评分与总满意度。结果干预前,两组患者的NIHSS评分比较,差异无统计学意义(P>0.05);干预后,观察组患者的NIHSS评分低于对照组,差异有统计学意义(P<0.05)。观察组患者中,发病6个月后经颅脑磁共振检查确认脑缺血再发生1例(1.92%),对照组8例(15.38%);观察组患者的脑缺血再发生率低于对照组,差异有统计学意义(P<0.05)。干预6个月后,观察组患者的生理功能、社会功能、精神健康、精力、一般健康状况评分均高于对照组,差异有统计学意义(P<0.05)。观察组患者的总满意度(96.15%)高于对照组(65.38%),差异有统计学意义(P<0.05)。结论RIPC实施后可有效改善脑梗死患者的预后效果,提高患者生活质量,降低脑缺血再发风险。Objective To discuss the influence of remote ischemic preconditioning(RIPC)on the prognosis of patients with cerebral infarction.Methods A total of 104 cerebral infarction patients treated in our hospital from January 2015 to January 2016 were selected as the research objects.Patients were divided into the observation group and the control group according to the computer random method,52 cases in each group.Patients in the observation group received conventional drug therapy combined with RIPC nursing intervention,and patients in the control group received conventional nursing+drug therapy.The national institutes of health stroke scale(NIHSS)scores of the two groups of patients before and after intervention were evaluated,and the cerebral ischemia recurrence rate,quality of life score,and total satisfaction were compared between the two groups.Results There was no significant difference in NIHSS score between the two groups of patients before intervention(P>0.05).After intervention,the NIHSS score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Among patients in the observation group,1 case(1.92%)of cerebral ischemia recurred confirmed by cranial magnetic resonance examination 6 months after attack,and 8 cases(15.38%)in the control group.The recurrence rate of cerebral ischemia in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).After 6 months of intervention,the physical function,social function,mental health,energy and general health status scores of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).The total satisfaction of patients in the observation group(96.15%)was higher than that in the control group(65.38%),and the difference was statistically significant(P<0.05).Conclusion The implementation of RIPC can effectively improve the prognosis of patients with cerebral infarction,improve the l

关 键 词：脑梗死 预后 肢体远隔缺血预适应 生活质量 脑缺血 精神健康 

分 类 号：R743[医药卫生—神经病学与精神病学]