2016年-2017年湖州地区食源性疾病病原菌检出分析  

Detection and analysis of pathogenic bacteria in food-borne diseases from 2016 to 2017 in Huzhou

作　　者：强鑫华 周丽华[1] 王萍[1] 嵇龙飞 郑莉莉 QIANG Xin-hua;ZHOU Li-hua;WANG Ping;JI long-fei;ZHENG Li-li(The First People's Hospital of Huzhou,Huzhou,Zhejiang 313000,China)

机构地区：[1]浙江省湖州市第一人民医院,浙江湖州313000

出　　处：《中国卫生检验杂志》2020年第9期1118-1120,共3页Chinese Journal of Health Laboratory Technology

基　　金：浙江省医药卫生青年人才项目(2019RC082);浙江省湖州市科技局项目(2017GY40)。

摘　　要：目的回顾性分析浙江省湖州市食源性疾病的发病特征以及病原菌的流行情况,为当地食源性疾病的防控、临床治疗提供科学依据。方法依据《浙江省食源性致病菌监测工作手册》,收集湖州市第一人民医院2016年-2017年共1 098份食源性腹泻患者粪便标本进行常规培养、血清凝集、PCR毒力基因检测分析。结果 1 098例食源性腹泻患者,共检出阳性333例,阳性率为30. 3%(333/1 098),其中分离到致泻性大肠埃希菌159株,占47. 7%(159/333);副溶血性弧菌76株,占22. 8%(76/333);嗜水/豚鼠气单胞菌51株,占15. 3%(51/333);沙门菌属45株,占13. 5%(45/333);河流弧菌2株,占0. 6%(2/333),未分离到志贺菌属及霍乱菌属。6月-9月为疾病高发时间,21岁~40岁年龄段为疾病高发人群。结论湖州地区食源性腹泻病原菌检出种类较多,以致泻性大肠埃希菌为主;阳性检出率较高;呈明显的季节性和年龄段分布,与周边城市有所不同,相关部门应做好相应防控措施。Objective To retrospectively analyze the incidence characteristics of food-borne diseases and the prevalence of pathogenic bacteria in Huzhou,Zhejiang Province,so as to provide scientific evidence for prevention,control and clinical treatment of local food-borne diseases.Methods According to the Zhejiang Foodborne Pathogens Monitoring Workbook,1098 samples of food-borne diarrhea patients in the First People’s Hospital of Huzhou from 2016 to 2017 were collected for routine culture,serum agglutination and the detection and analysis of PCR virulence.Results A total of 333 positive cases were detected in 1098 patients with foodborne diarrhea.The positive rate was 30.3%(333/1098),of which 159 strains of Escherichia coli were isolated,accounting for 47.7%(159/333).76 strains of Vibrio hemolyticus accounted for 22.8%(76/333);51 strains of Aeromonas guinea accounted for 15.3%(51/333);45 strains of Salmonella accounted for 13.5%(45/333);2 strains of Vibrio flu accounted for 0.6%(2/333),Shigella and Cholera bacteria were not detected.June-September is the time of high incidence of diseases,and people aged from 21 to 40 years old are the people with high incidence of diseases.Conclusion The types of diarrheagenic causing pathogens varied in Huzhou,mainly diarrheagenic E.coli(DEC).The identification rate of pathogens was higher,showed obviously seasonal and age variations and had differences from the surrounding cities.Some relevant departments should take appropriate prevention and control measures.

关 键 词：食源性疾病 病原菌 流行特征 

分 类 号：R181.3[医药卫生—流行病学]