腹膜透析液的器官保护作用  

Protective effect of peritoneal dialysate on multiple organ injury

作　　者：张志宏(综述) 俞雨生(审校) ZHANG Zhihong;YU Yusheng(National Clinical Research Center of Kidney Diseases,Jinling Hospital,Nanjing University School of Medicine,Nanjing 210016,China)

机构地区：[1]东部战区总医院国家肾脏疾病临床医学研究中心全军肾脏病研究所,南京210016

出　　处：《肾脏病与透析肾移植杂志》2020年第2期181-185,共5页Chinese Journal of Nephrology,Dialysis & Transplantation

摘　　要：腹膜透析液是含有渗透剂、缓冲碱和电解质的无菌溶液,是实现血液净化、纠正机体内环境紊乱的关键要素。研究发现透析液灌注腹腔后具有改善微循环、减轻水肿、调节淋巴回流、抑制炎症反应等直接的器官保护作用,并已在临床得到初步应用。本文综述该领域的研究现状及其应用进展。Peritoneal dialysate(PD)solution is an aseptic solution containing osmotic agent,buffer alkali and electrolyte,which is the key factor to realize blood purification and correct the disorder of the internal environment.It has been found that PD solution has a direct organ protective effect after infusion into the abdomen,including improving microcirculation,promoting lymphoid reflux,reducing edema,counteracting inflammatory reaction and so on.The discussion herein will review the current available literature on the research status and application progress in this field.

关 键 词：腹膜透析 腹腔复苏 休克 缺血-再灌注 

分 类 号：R73[医药卫生—肿瘤]