机构地区:[1]复旦大学附属眼耳鼻喉科医院,上海200031
出 处:《中华实验眼科杂志》2020年第5期421-426,共6页Chinese Journal Of Experimental Ophthalmology
基 金:国家自然科学基金面上项目(81870661);上海申康医院发展中心市级医院新兴前沿技术联合攻关项目(SHDC12018110)。
摘 要:目的评估SITA Faster视野策略在青光眼患者中的应用价值。方法采用诊断试验研究方法,收集2018年9月至2019年2月就诊于复旦大学附属眼耳鼻喉科医院的共72名测试者视野报告资料,其中正常人28人56眼,青光眼患者44例86眼,在正常人与青光眼患者中评估视野策略SITA Standard(SS)与SITA Fast(SF)、SS与SITA Faster(SFR)策略检测结果的一致性和便捷性。收集并记录被测试者每眼每种策略完成所需时间、视野指数(VFI)、平均缺损(MD)与模式偏差概率图中视野缺损概率<5%、<2%、<1%、<0.5%的缺陷点数量进行差异性、相关性和一致性检验。结果合并的总人群中,使用SF和SFR策略相对SS的标准化使用时间分别为(64±13)%和(44±10)%。在正常人和青光眼患者中,使用SS与SF策略、SS与SFR策略的VFI和MD值比较,差异均无统计学意义(均P>0.05)。在合并的总人群中,使用SS与SF策略、SS与SFR策略的VFI值和MD值均呈正相关(均r=0.99,P<0.01)。在正常人和青光眼患者中,使用SS与SF策略、SS与SFR策略的VFI、MD值一致性均较好。对模式偏差概率图中相应概率点数的比较结果显示,正常人群中使用不同视野策略的缺陷点数比较差异均无统计学意义(均P>0.05),但相关性和一致性均不高;青光眼患者中,除使用SFR策略模式偏差概率图P<0.5%缺陷点数比SS策略少,差异有统计学意义(Z=-2.28,P=0.02)外,青光眼患者使用不同策略的缺陷点数比较差异均无统计学意义(均P>0.05),相关性和一致性均较高。结论使用SFR策略较SF和SS策略节约了更多的检测时间,以SS为检测标准,除模式偏差图有部分差异之外,其检测的差异小,检查结果基本一致。Objective To evaluate the clinical application of the SITA faster(SFR)visual field strategy in glaucoma patients.Methods A diagnostic test was adopted.A total of 72 subjects who visited the Eye and ENT Hospital Affiliated to Fudan University during September 2018 to February 2019 were collected,including 28 normal subjects(56 eyes)and 44 glaucoma patients(86 eyes).The consistency and convenience of visual field tests were evaluated using SITA Standard(SS)and SITA Fast(SF),or SS and SITA Faster(SFR)in normal subjects and glaucoma patients.Test duration,visual field index(VFI),mean deviation(MD)and the number of defect points with probabilities of<5%,<2%,<1%,and<0.5%in the pattern deviation probability plots were recorded,and tested for difference,correlation and consistency.This study followed the Declaration of Helsinki.Written informed consent was obtained from all subjects prior to their entering the study cohort.The study protocol was approved by the Ethics Committee of the Eye and ENT Hospital of Fudan University.Results For all of the included subjects,the mean test durations of SF and SFR were(64±13)%and(44±10)%compared to that of SS,respectively.MD and VFI evaluated by SS and SF,or by SS and SFR,showed no significant difference in either the normal subjects or the glaucoma patients(all at P>0.05).Across all included subjects,the positive correlation and consistency of MD and VFI were good(r=0.99,P<0.01).However,for the results of the probability points in the pattern deviation probability blot,there was no difference among normal subjects,but the correlation and consistency were not good.In the deviation probability blot,there was a greater number of defect points of P<0.5%in glaucoma patients evaluated via SS compared to those evaluated by SFR,and the difference was statistically significant(Z=-2.28,P=0.02).Apart from this,the number of defect points in glaucoma patients showed no difference between SS and SF,or between SS and SFR,and the correlation and consistency were higher in glaucoma patients than
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